Podcast: How to Screen and Diagnose Cholestatic Liver Diseases

In this episode, HoChong Gilles of the Richmond VA Medical Center, and Alison Moe of Atlanta Gastroenterology discuss a practical, step-by-step approach to screening for and diagnosing cholestatic liver disease. The conversation reviews how to recognize a cholestatic liver test pattern, evaluate symptoms such as pruritus and jaundice, and confirm that an elevated alkaline phosphatase is hepatic in origin through fractionation and gamma-glutamyl transferase (GGT) testing. The experts explain how clinical history, medication and supplement use, laboratory findings, and imaging can help distinguish intrahepatic cholestasis from extrahepatic biliary obstruction. They also examine the roles of ultrasound, MRI/MRCP, endoscopic ultrasound, and ERCP when evaluating bile duct dilation, strictures, gallstones, primary sclerosing cholangitis, and possible malignancy. Additional topics include autoimmune testing for conditions such as primary biliary cholangitis, the importance of considering drug-induced liver injury and herbal supplements, and when a liver biopsy may be appropriate after a comprehensive noninvasive workup. This educational podcast provides gastroenterology and hepatology clinicians, advanced practice providers, and other healthcare professionals with a clear clinical framework for evaluating abnormal liver tests and identifying the underlying cause of cholestasis.

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Jaksot(164)

Linerixibat Medication Review

Christina Hanson, FNP, and Dr. Marcelo Kugelmas of South Denver Gastroenterology review linerixibat, an ileal bile acid transporter (IBAT) inhibitor, and its role in managing cholestatic pruritus in p...

22 Syys 13min

Podcast: Managing Fatigue and Pruritus in Your Patients With PBC

How can clinicians better recognize and manage itching and fatigue in primary biliary cholangitis (PBC)? In this podcast, hepatology clinicians from RUSH University Medical Center discuss the impact o...

15 Syys 15min

GHAPPcast: Recognizing and Managing Overt Hepatic Encephalopathy

Thank you to Salix for their support on this podcast episode. In this GHAPP podcast, host Christina Hanson, FNP, welcomes Janet Gripshover, DNP, FNP-BC, MBA, for a practical discussion on recognizing ...

18 Elo 48min

FAQ: Counseling Patients on Overt Hepatic Encephalopathy

Thank you to Salix for their support on this FAQ video module.In this FAQ video module, Natalie Oliver, PA-C, discusses how healthcare professionals can counsel patients and caregivers about overt hep...

11 Elo 4min

FAQ: Identifying & Diagnosing Overt Hepatic Encephalopathy

Thank you to Salix for their support on this FAQ video module. In this FAQ video module, Samantha Ramirez, NP-C, discusses how healthcare professionals can identify and diagnose overt hepatic encephal...

4 Elo 2min

Subgroup Analysis: Differences in Maintenance Dosing For UC and CD

Thank you to Johnson & Johnson for their support on this podcast episode. In this GHAPP podcast, Amy Stewart, NP, of Capital Digestive Care, introduces a practical inflammatory bowel disease discussio...

23 Heinä 7min

Medication Review: Efficacy & Safety of Risankizumab in Patients with Moderate to Severely Active UC

Thank you to AbbVie for their support of this Medication Review Video Module.In this medication review, Melissa Ferrari, PA, and Jennifer Hamilton, MSPAS, PA-C, provide a comprehensive overview of the...

30 Kesä 17min