171: Debunking the Continuous Progesterone Myth: Unopposed Estradiol Is the Real Concern with Phyllis Bronson, PhD Jill Chmielewski, RN, BSN, Carol Petersen, RPh, CNP

There is a lot of conflicting information online about progesterone right now, particularly around whether women need to take it continuously, whether cycling is necessary, and whether progesterone can somehow interfere with estrogen or increase dementia risk. In this conversation, Dr. Phyllis Bronson, Carol Petersen, RPh, CNP, and Jill Chmielewski, RN, BSN, discuss some of the biggest claims circulating about progesterone and hormone therapy.

The conversation explores the importance of progesterone, how different delivery methods can affect the way it works in the body, and why dose and individual response matter. They also discuss oral, topical and vaginal progesterone, the role of allopregnanolone, estriol and Bi-Est, and why measuring hormones in the blood doesn't always tell the full story of what is happening at the tissue level.

They also tackle one of the biggest current controversies: the idea that continuous progesterone may increase dementia risk. The group discusses the evidence and theories behind this claim, the importance of balancing estradiol with progesterone, and why women need to be cautious about making hormone decisions based on simplified social media messaging. This is a wide-ranging conversation designed to give you more context, more questions to ask, and a deeper understanding of the ongoing debate around women's hormones.

In this episode:

• The truth about continuous vs. cycling progesterone
• How progesterone works with estrogen in the body
• Oral, vaginal and transdermal progesterone: what's the difference?
• The controversy around progesterone and dementia risk
• Why hormone therapy needs to be individualized based on dose, delivery method and your unique response

About Phyllis Bronson, PhD

Phyllis Bronson, Ph.D., holds a doctorate in biochemistry. Her ongoing research involves studying the biological impact of molecules on mood and emotion. Dr. Bronson works with women who have hormone-based mood disorders, utilizing her original research on human identical hormones. She lives in Aspen, Colorado, and is President of Biochemical Consulting and The Biochemical Research Foundation. Dr. Bronson is the author of Moods, Emotions, and Aging: Hormones and the Mind-Body Connection,and has authored many articles, which can be found here.

In the Aspen area? On July 27th, the Jewish Community Center in Aspen will be hosting The Great Hormone Conversation with Phyllis and Dr. Alan Altman. For more info or tickets,click here.‍ ‍

About Carol Petersen, RPh, CNP

Carol Petersen is an accomplished compounding pharmacist with decades of experience helping patients improve their quality of life through bioidentical hormone replacement therapy. She graduated from the University of Wisconsin School of Pharmacy and is a Certified Nutritional Practitioner. Her passion for optimizing health and commitment to compounding is evident in her involvement with organizations including the International College of Integrated Medicine and the American College of Apothecaries, the Academy of Anti-Aging Medicine (A4M), American Pharmacists Association and the Alliance for Pharmacy Compounding.

She was also the founder and first chair for the Compounding Special Interest Group with the American Pharmacists Association. She chairs the Integrated Medicine Consortium, an umbrella group for complementary medicine organizations. She cohosts a radio program, "Take Charge of Your Health," in the greater New York area. She is on the Medical Advisory Boards for the Centre for Menstrual Cycle and Ovulation Research (CeMCOR.ca) and the Institute for Bioidentical Medicine (IOBIM.org). She also writes and edits for A4M's website www.worldhealth.net and is a co-producer of "Immortality Now" podcasts. Carol offers personal consultations at www.thewellnessbydesignproject.com.

About Jill Chmielewski, RN, BSN

Jill Chmielewski, a Registered Nurse, Certified Health Coach, Menopause Educator, and Women's Health Advocate with over 30 years of experience in healthcare.

Most recently, Jill joined the Balance App team as the U.S. expert. Balance was founded by Dr. Louise Newson and is dedicated to educating and empowering women around the world with evidence-based information, helping them better understand their hormone health and make informed choices for their bodies.