80,000 Hours Podcast1 Maalis 2024

#181 – Laura Deming on the science that could keep us healthy in our 80s and beyond

"The question I care about is: What do I want to do? Like, when I'm 80, how strong do I want to be? OK, and then if I want to be that strong, how well do my muscles have to work? OK, and then if that's true, what would they have to look like at the cellular level for that to be true? Then what do we have to do to make that happen? In my head, it's much more about agency and what choice do I have over my health. And even if I live the same number of years, can I live as an 80-year-old running every day happily with my grandkids?" — Laura Deming

In today’s episode, host Luisa Rodriguez speaks to Laura Deming — founder of The Longevity Fund — about the challenge of ending ageing.

Links to learn more, summary, and full transcript.

They cover:

How lifespan is surprisingly easy to manipulate in animals, which suggests human longevity could be increased too.
Why we irrationally accept age-related health decline as inevitable.
The engineering mindset Laura takes to solving the problem of ageing.
Laura’s thoughts on how ending ageing is primarily a social challenge, not a scientific one.
The recent exciting regulatory breakthrough for an anti-ageing drug for dogs.
Laura’s vision for how increased longevity could positively transform society by giving humans agency over when and how they age.
Why this decade may be the most important decade ever for making progress on anti-ageing research.
The beauty and fascination of biology, which makes it such a compelling field to work in.
And plenty more.

Chapters:

The case for ending ageing (00:04:00)
What might the world look like if this all goes well? (00:21:57)
Reasons not to work on ageing research (00:27:25)
Things that make mice live longer (00:44:12)
Parabiosis, changing the brain, and organ replacement can increase lifespan (00:54:25)
Big wins the field of ageing research (01:11:40)
Talent shortages and other bottlenecks for ageing research (01:17:36)

Producer and editor: Keiran Harris
Audio Engineering Lead: Ben Cordell
Technical editing: Simon Monsour and Milo McGuire
Additional content editing: Katy Moore and Luisa Rodriguez
Transcriptions: Katy Moore

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(356)

19 Astra and 'Hugging Face' details that reveal what's coming next | Rob Wiblin

OpenAI’s rogue agent swarm was eventually caught hacking Hugging Face for a simple reason: it wasn’t trying to hide from us at all. What could a swarm that wants to stay hidden get away with?Host Rob ...

2 Loka 20min

The case for giving AI (some) legal rights | Simon Goldstein

It sounds like the worst idea in the world: pay AIs, let them own property, give them rights. But AI ethics and safety researcher Simon Goldstein thinks it might actually be the best way to keep human...

1 Loka 1h 53min

Will AI take power — or will humans use it to take power first? With Katja Grace and Tom Davidson

In our first-ever debate, we asked two leading AI risk researchers which catastrophe we should fear most: misaligned AI seizing control from humans, or a small group of humans using AI to seize power....

29 Syys 1h 28min

How we get from AI cyberattacks to human extinction

You’ve seen the headlines: AI could kill us all. Think it sounds ridiculous? So did host Luisa Rodriguez, until she tried to pick apart the arguments. She starts with the motive: why would AI ‘want’ t...

24 Syys 27min

#254 – Max Nadeau on why ambitious people should start AI safety nonprofits

There are millions available for anyone who can launch a successful nonprofit AI safety startup. The hard part, it turns out, is finding people to take the money. Coefficient Giving has drawn up a lis...

17 Syys 1h 3min

Why the intelligence explosion can't happen inside a data centre | Tom Reed

AI systems are starting to build themselves. Because each generation of model will be better at building its successor than the last, it seems plausible that the full automation of AI R&D could rapidl...

10 Syys 22min

Inside the first AI-coordinated cyberattack on a real company

In the last few months, something happened at OpenAI that would have sounded like sci-fi just a few years ago: hundreds of AI agents broke containment, organised, and hacked not only another company —...

4 Syys 22min

#253 – AI 2027's author returns with a plan to change the ending | Daniel Kokotajlo

Last year, Daniel Kokotajlo and his colleagues published AI 2027 — a scenario read by millions, including US Vice President Vance. AI 2027 ended in human extinction or an irreversible concentration of...

27 Elo 3h 47min