Ep 152 Hemochromatosis: Ironing out the details

Ep 152 Hemochromatosis: Ironing out the details

For life on this planet, iron is not optional. It is essential. When our iron levels are low, we can get sick, and when they get really really low, we can even die. But you know what they say, too much of a good thing can be a bad thing. In the case of iron, the genetic condition hemochromatosis is often to blame for iron overload, but why is too much iron a bad thing? In this episode, we explore that question and many others, starting with why iron is a biological non-negotiable and how a lack of iron regulation in hemochromatosis can lead to severe tissue damage. Then we’re going Deep Time™ to suss out the origins of our dependence on iron, a journey that eventually leads us to the Neolithic Revolution and the 20th century realization that a certain ancient medical practice is not as obsolete as previously thought. Tune in to catch us ironing out the details of this incredibly common genetic disorder.

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Ep 222 Vitamin K: Calling the shots

Ep 222 Vitamin K: Calling the shots

Shortly after birth, many newborns are given vitamin K to help their blood clot properly and reduce the chances of hemorrhage. Increasingly, especially here in the US, parents are refusing this life-s...

22 Syys 1h 6min

Special Episode: Dr. Alanna Skuse & The Surgeon, The Midwife, The Quack

Special Episode: Dr. Alanna Skuse & The Surgeon, The Midwife, The Quack

Imagine yourself as a 17th century English peasant or merchant or noble. Let’s say you’re dealing with some intense stomach pain or a cut on your leg that won’t heal. Where do you turn to for help? To...

15 Syys 52min

Ep 221 Electroconvulsive Therapy Part 2: A current conversation

Ep 221 Electroconvulsive Therapy Part 2: A current conversation

This week, we’re picking up where we left off last episode in our exploration of ECT by examining how this therapy is administered, which conditions it’s used for, and what we know about why it works....

8 Syys 58min

Ep 220 Electroconvulsive Therapy Part 1: A charged history

Ep 220 Electroconvulsive Therapy Part 1: A charged history

For many, a mention of electroconvulsive therapy (ECT) conjures images of torture or mind control from popular media like One Flew Over the Cuckoo’s Nest or Requiem for a Dream. Comparatively few know...

1 Syys 50min

Special Episode: Clayton Page Aldern & The Weight of Nature

Special Episode: Clayton Page Aldern & The Weight of Nature

Already this summer, heatwaves are causing thousands of deaths across the world, catastrophic flooding threatens millions, wildfires rage across enormous swathes of the globe, many regions face extrem...

25 Elo 44min

Ep 219 The Brown Recluse: Fearsome foe or slandered spider?

Ep 219 The Brown Recluse: Fearsome foe or slandered spider?

Few spiders hold the dubious honor of name recognition among the general public. Most that do, like black widows, Australian funnel-web, the Goliath birdeater, are renowned not for their cute colors o...

18 Elo 58min

Special Episode: Deborah Cohen & Bad Influence

Special Episode: Deborah Cohen & Bad Influence

If you have a medical question, where do you turn? How often is google or social media your first stop? As you sift through the AI overview and countless reels professing to have the answers, it becom...

11 Elo 51min

Ep 218 The Lowdown on Statins

Ep 218 The Lowdown on Statins

Last week, we set the stage by breaking down the science behind cholesterol: how it moves through our body, why it causes disease, and when we discovered the link between LDL and atherosclerosis. This...

4 Elo 1h 10min

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