a16z Podcast: Connecting Hearts, Bodies, and Networks to Cure Cancer
a16z Podcast26 Tammi 2019

a16z Podcast: Connecting Hearts, Bodies, and Networks to Cure Cancer

Veterinary oncology can inform human oncology, and vice versa -- providing a better model for looking at drug performance, interrelationships, and more. Especially when you add in data (there's no "doggy HIPAA!") and networks to get a "living laboratory at scale".

Or so argues Amy Abernethy (Chief Medical and Chief Scientific Officer at Flatiron Health and advisor to One Health), who was recently named the new Principal Deputy Commissioner of the FDA, pending ethics clearance; and Christina Lopes, CEO and co-founder of One Health; in conversation with a16z bio general partner Jorge Conde. Dogs -- as a species, as pets, as companions, as family members -- evolved alongside humans, so are actually more similar to us... not just genetically and in terms of the biologic pathways that may cause cancer, but also in exposure to similar environmental factors as well.

But what does this all mean when it comes to thinking about real-world evidence in science, human clinical trials, and more broadly, building a bio company? How can product designers -- of all kinds -- backwards-architect their product roadmap for data network effects? And how can bio founders keep both a big-picture roadmap in mind while also focusing on specific milestones, and while working across unconnected disciplines as well? We cover all this and more in this special episode of the a16z Podcast, recorded during the recent J.P.M. healthcare conference in San Francisco.

The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.

This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/.

Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

Jaksot(916)

a16z Podcast: Demystifying Venture Capital

a16z Podcast: Demystifying Venture Capital

What do venture capitalists actually do all day? And what is the path that leads to a career investing in startups? Hummer Winblad’s Ann Winblad, Cowboy Ventures' Aileen Lee, Aspect Ventures' Theresia Gouw, Intel Capital veteran and UPWARD founder Lisa Lambert, and Andreessen Horowitz’s Margit Wennmachers discuss VC trends, the importance of technical chops, and how to build the next generation of entrepreneurs and investors. And finally, in front of an appreciative crowd attending the UPWARD event at a16z, Ann Winblad reveals the secret to truly kicking ass.

2 Touko 201437min

a16z Podcast: When Your PC Expires, What's Next?

a16z Podcast: When Your PC Expires, What's Next?

Computing is in the midst of a transformation that puts your future device purchases up for grabs. It’s a safe bet that everyone will have a phone, and as the last holdouts switch over, that will inevitably mean a smartphone. But when your PC finally gives up the ghost, are you going to buy another PC? Perhaps a tablet? Or will another large screen device –a really big phone - be the ticket? Maybe just get all three? Benedict Evans and Steven Sinofsky discuss why laptops and tablets are competing for the same customers, and why it’s never wise to defend any form-factor to the death.

30 Huhti 201416min

a16z Podcast: Apple and the Fate of Tablets

a16z Podcast: Apple and the Fate of Tablets

Apple’s recent earnings sent the stock soaring. What drove that investor exuberance had everything to do with iPhone sales (and the China market), and very little to do with the iPad – the sales of which were essentially flat over the past year. Chris Dixon and Benedict Evans look at the fortunes of the world’s best-selling tablet, and what that means for the balance of power in the computing world. Are smartphones supplanting tablets for most uses? Are developers so focused on creating apps for the latest handsets the tablet is becoming an afterthought?

25 Huhti 201421min

a16z Podcast: The Future Of Television

a16z Podcast: The Future Of Television

Can technology companies show up and disrupt television with an onslaught of new gizmos and services, or is content still the controlling factor? What will it take in terms of money, business model and time to upend the TV model that has stubbornly persisted for decades? Will the old platforms and players dominate, or is now the time for new players to take charge? Andreessen Horowitz’s Benedict Evans and Zal Bilimoria discuss the future of television.

18 Huhti 201419min

a16z Podcast: Engineering a Revolution at Work

a16z Podcast: Engineering a Revolution at Work

From file cabinets to typewriters, spreadsheets and word processing the tools we use for work change not only what we do, but the culture of our workplace. Steven Sinofsky, a veteran of building software tools for productivity, discusses the latest revolution in technology-enabled tools with Benedict Evans. Why today’s cloud-based tools change the role of managers, and why the perfect tool will never exist (nor would you want it to).

10 Huhti 201423min

a16z Podcast: China and Tech

a16z Podcast: China and Tech

China has been a tough market to crack for U.S. internet companies. One of the key reasons is China has its own crop of hugely successful and highly innovative companies. Andreessen Horowitz’s Chris Dixon, Connie Chan and Benedict Evans highlight the key players in China, and what non-Chinese companies can learn from them. Where Chinese companies and money are headed next.

30 Maalis 201417min

a16z Podcast: Oculus and the (Mind-Blowing) Reality of Virtual Reality

a16z Podcast: Oculus and the (Mind-Blowing) Reality of Virtual Reality

Up until now virtual reality has been a disappointment for all those people pining for their own personal holodeck. But advances in the components required to create a truly immersive digital 3D experience have finally broken through much of what has been holding virtual reality back. As a consequence, Oculus VR is building something that is nothing short of a new medium. Andreessen Horowitz’s Chris Dixon, Balaji Srinivasan and Gil Shafir discuss the present and future potential of virtual reality. Take heart, the holodeck can’t be far away now.

28 Maalis 201412min

a16z Podcast: The Rise of Full Stack Startups

a16z Podcast: The Rise of Full Stack Startups

Suppose you develop a new technology that is valuable to some industry. The old approach was to sell or license your technology to the existing companies in that industry. The new approach is to build a complete, end-to-end product or service that bypasses existing companies. Andreessen Horowitz’s Chris Dixon, Balaji Srinivasan and Benedict Evans discuss the reasons behind, and advantages of, going “full stack.”

27 Maalis 201418min

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