a16z Podcast: The Biology of Pain
a16z Podcast17 Syys 2019

a16z Podcast: The Biology of Pain

What is the nature of physical pain? Why do we even experience it? Is there one type, or many? Do people experience pain differently? What is happening in our brains and our bodies when we experience pain? What is the biological link between pain and addiction? In this episode Clifford Woolf, Professor of Neurobiology at Harvard Medical School and a renowned expert on understanding pain, shares with with a16z's Hanne Tidnam all we know about the biology of pain.

Technology is enabling a new, deeper, and much more complex understanding of pain—which pathways and neurons are activated in the brain when, what patterns might represent which experiences of pain. We now understand that the notion of pain as a simple switch that can be switched on or off (you have pain/you don't have pain) and measured by categories like mild, moderate, or severe is just incorrect. Woolf describes the 4 different broad types of pain we in fact experience, what the purpose of each is, and what it means now that we can phenotype them and begin to understand them as distinct. Now that we have this deeper and much more complex understanding of pain, what does it mean for how we can treat pain in the future, and where we can intervene?

Jaksot(917)

a16z Podcast: The Rise of Full Stack Startups

a16z Podcast: The Rise of Full Stack Startups

Suppose you develop a new technology that is valuable to some industry. The old approach was to sell or license your technology to the existing companies in that industry. The new approach is to build a complete, end-to-end product or service that bypasses existing companies. Andreessen Horowitz’s Chris Dixon, Balaji Srinivasan and Benedict Evans discuss the reasons behind, and advantages of, going “full stack.”

27 Maalis 201418min

a16z Podcast: Searching for Mobile’s Own PageRank

a16z Podcast: Searching for Mobile’s Own PageRank

The mobile experience is still in its 1995 Yahoo phase, a sea of apps and websites without an easy way to find what you want and need on your smartphone. What will be mobile’s version of PageRank, the algorithm that made the web manageable? What is the interaction model and the form - app, card, URL – that will help us find, explore and engage with people, products and services from our mobile devices? Andreessen Horowitz’s Chris Dixon, Benedict Evans and Balaji Srinivasan delve into the options.

24 Maalis 201412min

a16z Podcast: Where is the Technology That "Matters?" Right Here

a16z Podcast: Where is the Technology That "Matters?" Right Here

There is a recurring theme that the tech industry is busy cranking out fluffy social apps rather than hardcore technology. Not the case, say Chris Dixon, Benedict Evans and Balaji Srinivasan. Not only are tech entrepreneurs going after the deficiencies in healthcare, transportation, finance, energy - you name it - with new approaches riding on top of sophisticated technologies, what looks like fluff today often wields some serious influence tomorrow.

21 Maalis 201414min

a16z Podcast: The State of the Bitcoin Ecosystem, and a Theory on Satoshi

a16z Podcast: The State of the Bitcoin Ecosystem, and a Theory on Satoshi

Andreessen Horowitz's Chris Dixon and Balaji Srinivasan discuss the state of the Bitcoin ecosystem now that the Mt. Gox dust has settled. What's next in crypto-currency, and a theory on Bitcoin creator Satoshi (not Dorian) Nakamoto.

20 Maalis 201415min

a16z Podcast: Apple and Google Won the Mobile OS War, But a New War Has Already Begun

a16z Podcast: Apple and Google Won the Mobile OS War, But a New War Has Already Begun

Apple and Google won the mobile OS war, but the next war – to build big businesses on top of Android and iOS – is just beginning. Andreessen Horowitz Partner Benedict Evans untangles what the next phase of mobile means for entrepreneurs, Apple and Google's competitors, and consumers eager for the next great gadget.

13 Maalis 201427min

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