Are 49ers ready for prime time vs. Bills with odds stacked against them?

Are 49ers ready for prime time vs. Bills with odds stacked against them?

Matt Maiocco and Jennifer Lee Chan discuss the 49ers' mounting injuries entering their prime-time matchup with the Bills on NBC's "Sunday Night Football," including a previously undisclosed ankle fracture to star linebacker Fred Warner. Matt and Jennifer also analyze which three players on offense and defense have performed lower or been available significantly less compared to their standout 2023 seasons. Later, Matt and Greg Papa discuss if inclement weather will play a role in Buffalo, as well as keys to San Francisco making the Week 13 matchup competitive.

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(1:00) 49ers injury updates

(10:00) Comparing 2023 49ers to 2024 team, which mathematically is still in the playoff hunt

(13:00) Offensive, defensive players whose production fell significantly between last season and this season

(22 :00) How inclement weather in Buffalo could affect SNF game

(24:00) Which backup QB should play if Purdy sits out again?

(32:00) Keys to 49ers coming out competitive vs. Bills

Jaksot(805)

77. 49ers: Jerick McKinnon

77. 49ers: Jerick McKinnon

49ers: New 49ers running back Jerick McKinnon, who replaced Carlos Hyde in free agency, already appears to be a great fit for Kyle Shanahan's offense and what the organization is looking to build.

22 Touko 201828min

76. 49ers: Dante Pettis

76. 49ers: Dante Pettis

76: 49ers: Wide receiver/return man Dante Pettis, the 49ers' second-round draft pick, had to prove to NFL teams that his outside interests has no significance when it comes to his passion for football.

15 Touko 201828min

75. 'One of the Great Mysteries' – The story of three 49ers diagnosed with ALS

75. 'One of the Great Mysteries' – The story of three 49ers diagnosed with ALS

49ers: The re-release of a podcast during ALS Awareness Month. Matt Hazeltine, Gary Lewis, Bob Waters and Dwight Clark each spent a lot of time on the same practice field in Redwood City. Former team owner Eddie DeBartolo plans to commission a study.

8 Touko 201843min

74. 49ers: First-round draft pick Mike McGlinchey

74. 49ers: First-round draft pick Mike McGlinchey

49ers: Notre Dame offensive tackle Mike McGlinchey, the team's first-round pick, joins Matt Maiocco to discuss draft night and his eagerness to get to work with his new team.

1 Touko 201822min

73. 49ers: George Kittle

73. 49ers: George Kittle

49ers: George Kittle recalls going through the draft process a year ago and looks back on a rookie season in which he caught 43 passes for 515 yards and two TDs.

24 Huhti 201821min

72: 49ers: Marcus Lattimore talks about football and life skills

72: 49ers: Marcus Lattimore talks about football and life skills

49ers: Marcus Lattimore, who wants to eventually become an NFL general manager, talks about the Reuben Foster situations and a lot more on The 49ers Insider Podcast presented by Evergood Sausage Company.

17 Huhti 201831min

71. 49ers: Ian Williams discusses career-ending ankle condition

71. 49ers: Ian Williams discusses career-ending ankle condition

49ers: Former nose tackle Ian Williams' promising NFL career came to an abrupt end in the spring of 2016 due to an infection that developed in his twice-fractured ankle.

10 Huhti 201833min

70. 49ers: Answering post-free agency/pre-draft questions

70. 49ers: Answering post-free agency/pre-draft questions

49ers: Going to Twitter to answer questions about the 49ers' offseason.

3 Huhti 201824min

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