Uncontrolled Spread: Science, Policy, Institutions, Infrastructure
a16z Podcast20 Syys 2021

Uncontrolled Spread: Science, Policy, Institutions, Infrastructure

There's no question technology played a huge role in the recent/current pandemic, including especially in the plug-and-play engineering and incredibly fast development behind the mRNA vaccines... But is there an even bigger role for the private sector, not just government, to play (and partner) when it comes to key infrastructure for future such emergencies, and even beyond?

Especially given how faulty the translation of institutional science to policy and public health measures turned out to be -- for instance, with "6 feet" of social distancing, or with fomite (vs. aerosol) transmission of COVID. And why are we still talking about the same, not specific, vaccine booster for the Delta variant? What can we learn about real-world evidence, other clinical trial approaches, and progressive (vs. binary) EUA approvals when it comes to public health emergencies? Are capabilities like genomic surveillance and mapping strains -- which require layers of technology, real time -- sitting in the right places?

In this special book-launch episode of the a16z Podcast, former FDA commissioner Dr. Scott Gottlieb -- author of the upcoming new book, Uncontrolled Spread: Why COVID-19 Crushed Us, and How We Can Defeat the Next Pandemic -- shares insights on the above, and revealing stories from behind the scenes. Do we need a new entity to manage public health through a national security lens, and is the government capable? Gottlieb debates this and other probing questions from a16z co-founder Marc Andreessen (who famously wrote "It's time to build"); a16z bio general partner Vineeta Agarwala MD, Phd (who has spoken about the trials of clinical trials, practiced medicine during the pandemic, and more); and founding a16z bio general partner Vijay Pande PhD (who, among other things, founded the distributed computing project Folding@Home which pivoted to COVID proteins).

One thing's for sure -- with this COVID crisis, we're at an inflection point between old and new technology -- whether it's in how we make vaccines, or how we apply the fields of synthetic biology and genetic epidemiology in public health response. So now's the time to look both backward, and forward, to really change things...

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.


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a16z Podcast: The Two Big Problems With Thomas Piketty’s “Capital in the Twenty-First Century”

a16z Podcast: The Two Big Problems With Thomas Piketty’s “Capital in the Twenty-First Century”

“At a moment of great concern about inequality, now comes a learned tome proclaiming the gravity of the inequality problem,” says Larry Summers in a conversation with Andreessen Horowitz’s Balaji Srinivasan. “It’s a stunning thing, and it must reflect positively on the growing intellectualism of the society that a book like that could be a best-seller.” But that doesn’t mean Piketty got it right, adds the former Secretary of the Treasury and current a16z special advisor. Summers describes the two big problems he sees with Piketty’s argument, and how the forces of technology and globalization are better lenses through which to view and explain income inequality. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

15 Touko 201415min

a16z Podcast: Demystifying Venture Capital

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2 Touko 201437min

a16z Podcast: When Your PC Expires, What's Next?

a16z Podcast: When Your PC Expires, What's Next?

Computing is in the midst of a transformation that puts your future device purchases up for grabs. It’s a safe bet that everyone will have a phone, and as the last holdouts switch over, that will inevitably mean a smartphone. But when your PC finally gives up the ghost, are you going to buy another PC? Perhaps a tablet? Or will another large screen device –a really big phone - be the ticket? Maybe just get all three? Benedict Evans and Steven Sinofsky discuss why laptops and tablets are competing for the same customers, and why it’s never wise to defend any form-factor to the death. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

30 Huhti 201416min

a16z Podcast: Apple and the Fate of Tablets

a16z Podcast: Apple and the Fate of Tablets

Apple’s recent earnings sent the stock soaring. What drove that investor exuberance had everything to do with iPhone sales (and the China market), and very little to do with the iPad – the sales of which were essentially flat over the past year. Chris Dixon and Benedict Evans look at the fortunes of the world’s best-selling tablet, and what that means for the balance of power in the computing world. Are smartphones supplanting tablets for most uses? Are developers so focused on creating apps for the latest handsets the tablet is becoming an afterthought? Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

25 Huhti 201421min

a16z Podcast: The Future Of Television

a16z Podcast: The Future Of Television

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18 Huhti 201419min

a16z Podcast: Engineering a Revolution at Work

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10 Huhti 201423min

a16z Podcast: China and Tech

a16z Podcast: China and Tech

China has been a tough market to crack for U.S. internet companies. One of the key reasons is China has its own crop of hugely successful and highly innovative companies. Andreessen Horowitz’s Chris Dixon, Connie Chan and Benedict Evans highlight the key players in China, and what non-Chinese companies can learn from them. Where Chinese companies and money are headed next. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

30 Maalis 201417min

a16z Podcast: Oculus and the (Mind-Blowing) Reality of Virtual Reality

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28 Maalis 201412min

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