This Podcast Will Kill You26 Touko 2020

Ep 51 The Path of Most (Antibiotic) Resistance

No story of antibiotics would be complete without the rise of resistance. As promised in our last episode, this week we dive into what the WHO calls ‘one of the biggest threats to global health, food security, and development today’ - antibiotic resistance. In the decades since their development, misuse and overuse of antibiotics has led to many becoming all but useless, and our world seems on the verge of plunging into a post-antibiotic era. How does resistance work? Where did it come from? Why did it spread so far so rapidly? Is there any hope? In this episode, we answer all these questions and more. First, we explore the many ways bacteria evade the weaponry of antibiotic compounds. Then we trace the global spread of these resistant bugs by examining the major contributors to their misuse and overuse. And finally we assess the current global status of antibiotic resistant infections (spoiler: it’s very bad) and search for any good news (spoiler: there’s a lot!). To chat about one super cool and innovative alternative to antibiotics, we are joined by the amazing Dr. Steffanie Strathdee (Twitter: @chngin_the_wrld), Associate Dean of Global Health Sciences, Harold Simon Professor at the University of California San Diego School of Medicine and Co-Director at the Center for Innovative Phage Applications and Therapeutics. Dr. Strathdee provides a firsthand account of helping her husband, Dr. Tom Patterson, fight off a deadly superbug infection by calling on a long-forgotten method of treating bacterial infections: phage therapy.

To read more about phage therapy and Dr. Strathdee’s incredible experiences, check out The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir.

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Ep 222 Vitamin K: Calling the shots

Shortly after birth, many newborns are given vitamin K to help their blood clot properly and reduce the chances of hemorrhage. Increasingly, especially here in the US, parents are refusing this life-s...

22 Syys 1h 6min

Special Episode: Dr. Alanna Skuse & The Surgeon, The Midwife, The Quack

Imagine yourself as a 17th century English peasant or merchant or noble. Let’s say you’re dealing with some intense stomach pain or a cut on your leg that won’t heal. Where do you turn to for help? To...

15 Syys 52min

Ep 221 Electroconvulsive Therapy Part 2: A current conversation

This week, we’re picking up where we left off last episode in our exploration of ECT by examining how this therapy is administered, which conditions it’s used for, and what we know about why it works....

8 Syys 58min

Ep 220 Electroconvulsive Therapy Part 1: A charged history

For many, a mention of electroconvulsive therapy (ECT) conjures images of torture or mind control from popular media like One Flew Over the Cuckoo’s Nest or Requiem for a Dream. Comparatively few know...

1 Syys 50min

Special Episode: Clayton Page Aldern & The Weight of Nature

Already this summer, heatwaves are causing thousands of deaths across the world, catastrophic flooding threatens millions, wildfires rage across enormous swathes of the globe, many regions face extrem...

25 Elo 44min

Ep 219 The Brown Recluse: Fearsome foe or slandered spider?

Few spiders hold the dubious honor of name recognition among the general public. Most that do, like black widows, Australian funnel-web, the Goliath birdeater, are renowned not for their cute colors o...

18 Elo 58min

Special Episode: Deborah Cohen & Bad Influence

If you have a medical question, where do you turn? How often is google or social media your first stop? As you sift through the AI overview and countless reels professing to have the answers, it becom...

11 Elo 51min

Ep 218 The Lowdown on Statins

Last week, we set the stage by breaking down the science behind cholesterol: how it moves through our body, why it causes disease, and when we discovered the link between LDL and atherosclerosis. This...

4 Elo 1h 10min