Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

The 49ers' home opener against the Arizona Cardinals brought plenty of twists and turns as San Francisco emerged victorious to maintain its undefeated start with a thrilling 16-15 win. Kicker Eddy Piñeiro's game-winning field goal and Mac Jones' clinical two-minute drive got the 49ers over the hump in a gutsy win, improving San Francisco to 3-0 in the 2025 season. The win didn't come without its costs as star defensive end Nick Bosa exited the game with an apparent knee injury. Matt Maiocco and Jennifer Lee Chan break down the 49ers' courageous victory, Bosa's injury and how San Francisco's alleged weakness in depth has turned into their strength as they now sit atop the NFC West standings.

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(1:00) Uncommon scoreline, but 49ers are making these kinds of win common
(3:00) Nick Bosa injury update
(6:00) Eddy Piñeiro delivers in the clutch
(10:00) Mac Jones seems to rise to the occasion
(12:00) 49ers' defense is putting the team on their back
(30:00) Robert Saleh has been the key to unlocking 49ers' defense


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39. 49ers: John Lynch discusses his approach to GM duties from his second-story office

39. 49ers: John Lynch discusses his approach to GM duties from his second-story office

49ers: General manager John Lynch’s perspective of handling cuts shaped by his experiences as a player. (Episode 39) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

6 Syys 201742min

38. 49ers: Meet some of the undrafted rookies making serious bids for roster spots

38. 49ers: Meet some of the undrafted rookies making serious bids for roster spots

49ers: There are few things in the NFL more tenuous than the careers of undrafted rookies. Six of those players -- Erik Magnuson, Matt Breida, Lorenzo Jerome, Victor Bolden, Cole Hikutini and Tyler McCloskey -- share their thoughts as the regular season approaches. (Episode 38) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

29 Elo 201735min

37. 49ers: Defensive coordinator Robert Saleh talks about how 9/11 inspired him to coach

37. 49ers: Defensive coordinator Robert Saleh talks about how 9/11 inspired him to coach

49ers: First-year defensive coordinator Robert Saleh discusses the mindset and system he is bringing to Kyle Shanahan’s coaching staff. (Episode 37) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

25 Elo 201732min

36. 49ers coach Kyle Shanahan has confidence his team “will be able to surprise some people”

36. 49ers coach Kyle Shanahan has confidence his team “will be able to surprise some people”

49ers: Kyle Shanahan is comfortable talking football, and that’s what he does as he takes part in this edition of the 49ers Insider Podcast. (Episode 36) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

8 Elo 201736min

35. 49ers: Two-time Super Bowl-winning coach George Seifert enjoys well-earned retirement

35. 49ers: Two-time Super Bowl-winning coach George Seifert enjoys well-earned retirement

49ers: George Seifert’s defensive influence is being felt once again with his former team via Pete Carroll’s Seattle scheme. (Episode 35) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

3 Elo 201733min

34. 49ers: Matt Barrows of the Sacramento Bee joins Matt Maiocco to talk about their profession and preview training camp

34. 49ers: Matt Barrows of the Sacramento Bee joins Matt Maiocco to talk about their profession and preview training camp

49ers: Longtime beat reporters Matt Maiocco and Matt Barrows discuss the first training camp of Kyle Shanahan and John Lynch, as well as many other topics. (Episode 34) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

25 Heinä 201750min

33. 49ers: Carmen Policy relives ‘90s rivalry with Cowboys, makes comparison to Warriors-Cavaliers

33. 49ers: Carmen Policy relives ‘90s rivalry with Cowboys, makes comparison to Warriors-Cavaliers

Former 49ers president Carmen Policy calls the Warriors the new "gold standard" of sports franchises and believes his old team is on the right track with Kyle Shanahan and John Lynch. (Episode 33) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

6 Kesä 201758min

32. 49ers: QB Matt Barkley did not have to wait long this offseason to end up in a familiar system

32. 49ers: QB Matt Barkley did not have to wait long this offseason to end up in a familiar system

49ers: NBC Sports Bay Area’s Mindi Bach and Matt Maiocco preview Matt Barkley’s first interview since signing on to become Kyle Shanahan’s backup quarterback. (Episode 32) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

18 Touko 201741min

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