Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

The 49ers' home opener against the Arizona Cardinals brought plenty of twists and turns as San Francisco emerged victorious to maintain its undefeated start with a thrilling 16-15 win. Kicker Eddy Piñeiro's game-winning field goal and Mac Jones' clinical two-minute drive got the 49ers over the hump in a gutsy win, improving San Francisco to 3-0 in the 2025 season. The win didn't come without its costs as star defensive end Nick Bosa exited the game with an apparent knee injury. Matt Maiocco and Jennifer Lee Chan break down the 49ers' courageous victory, Bosa's injury and how San Francisco's alleged weakness in depth has turned into their strength as they now sit atop the NFC West standings.

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(1:00) Uncommon scoreline, but 49ers are making these kinds of win common
(3:00) Nick Bosa injury update
(6:00) Eddy Piñeiro delivers in the clutch
(10:00) Mac Jones seems to rise to the occasion
(12:00) 49ers' defense is putting the team on their back
(30:00) Robert Saleh has been the key to unlocking 49ers' defense


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146. 49ers: CEO Jed York

146. 49ers: CEO Jed York

49ers: CEO Jed York discusses the organization's decision to have the club practice this week in his hometown of Youngstown, Ohio. York talks about what it was like growing up in Northeast Ohio, the relationship between coach Kyle Shanahan and GM John Lynch, and looks ahead to inducting Terrell Owens into the 49ers Hall of Fame. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

12 Syys 201918min

145: 49ers: Pro Football Hall of Fame President David Baker

145: 49ers: Pro Football Hall of Fame President David Baker

49ers: The 49ers are spending the week in Youngstown, Ohio, as they prepare for Week 2 against the Cincinnati Bengals. Canton, site of the Pro Football Hall of Fame, is just an hour away, so we took a trip to tour the museum, see the bronze busts, and visit with HOF President David Baker. Also, Laura Britt makes her return. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

11 Syys 201936min

144. 49ers: Linebacker Azeez Al-Shaair

144. 49ers: Linebacker Azeez Al-Shaair

49ers: Rookie linebacker Azeez Al-Shaair explains why he hates being labeled as an undrafted free agent, but also how the uphill struggle fits perfectly into the book that is his life. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

3 Syys 201924min

143. 49ers: Cornerback Richard Sherman

143. 49ers: Cornerback Richard Sherman

49ers: Richard Sherman talks about his optimism for the upcoming season, being healthy again, his motivation for playing the sport, the reaction to Andrew Luck's retirement and much, much more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

28 Elo 201923min

142. 49ers: Wrapping up preseason Week 2 in Denver

142. 49ers: Wrapping up preseason Week 2 in Denver

49ers: Raheem Mostert, Mitch Wishnowsky, Kentavius Street, Dontae Johnson and Broncos coach Vic Fangio chat with Matt Maiocco, who also discusses the team's trip to Denver with Jennifer Lee Chan. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

20 Elo 201921min

141. 49ers: Peter King

141. 49ers: Peter King

49ers: Peter King of Football Morning in America and the Peter King Podcast joins NBC Sports colleague Matt Maiocco as his summer tour of NFL training camps made its swing through Santa Clara. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

15 Elo 201928min

140. 49ers: Preseason update with Nick Mullens, Adrian Colbert

140. 49ers: Preseason update with Nick Mullens, Adrian Colbert

49ers: Few of the team's projected starters suited up for the preseason opener against the Dallas Cowboys. Now, the 49ers travel to Denver for two big days of practices against the Broncos and their second preseason game on Monday night. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

13 Elo 201916min

139: 49ers: Greg Papa

139: 49ers: Greg Papa

49ers: Greg Papa, the new radio play-by-play voice of the team, shares insight into his craft and his views on QB Jimmy Garoppolo and his expectations for this year's team. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

6 Elo 201936min

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