Pathophysiology of Obesity, Part 6 - The Gut-Brain Conversation
Our gut constantly talks to our brain through a symphony of hormones that control hunger, fullness, and energy balance. Some hormones rev up appetite, while others apply the brakes.In this episode, we...
31 Maalis 4min
Pathophysiology of Obesity, Part 5 - Insulin: The Gatekeeper
When people say "I'm doing everything right, but the weight won't come off," the answer often lies in insulin resistance.Insulin is the key that unlocks your cells so glucose can enter. Once inside, y...
26 Maalis 6min
Pathophysiology of Obesity, Part 4 — Leptin: The Broken Thermostat
In 1994, scientists discovered leptin, a hormone made by fat cells that tells your brain you've had enough to eat. They thought it was the cure for obesity.But here's the twist: most people with obesi...
24 Maalis 5min
Pathophysiology of Obesity, Part 3 — The Hormonal Storm
Obesity isn't just about food and calories. It's about a highly complex network of hormones that tells you when to eat, when to stop, and how much energy to burn. When that system gets disrupted, ever...
19 Maalis 5min
Pathophysiology of Obesity, Part 2 — Epigenetics: Your Genes Aren't Your Destiny
In the last episode, we talked about how genetics play a huge role in obesity — shaping metabolism, appetite, and fat storage. But here's the catch: your genes aren't your destiny.Today, we're diving ...
17 Maalis 4min
Pathophysiology of Obesity, Part 1 — It's Genetics, Not Willpower
Let me start by explaining what "pathophysiology" actually means — because this word gets thrown around in medicine all the time, and it's worth understanding.Physiology is how the body normally works...
17 Maalis 6min
Morbidity and Mortality — The Real Cost of Untreated Obesity
This episode is about understanding what's really at stake when obesity goes untreated — not to scare you, but to give you clarity on why this work matters so much.Let me start by explaining two criti...
10 Maalis 6min
The Stigma Around Obesity | Weight and Metabolism with Dr. Deepti Sharma
Let's talk about something that doesn't get addressed enough: the stigma, bias, and discrimination that people with obesity face every single day.Obesity stigma exists because of oversimplification, c...
5 Maalis 3min
