Marjolin's Ulcer: When a Chronic Wound Turns Cancerous

Marjolin's Ulcer: When a Chronic Wound Turns Cancerous

Dr. G explains Marjolin ulcer, a form of squamous cell carcinoma that can arise in long-standing, chronically inflamed or scarred wounds—especially diabetic foot ulcers—and why early recognition matters for limb salvage and survival.

Key signs include changing or hypertrophic margins, rolled or friable edges, unexplained bleeding, disproportionate pain, non-healing despite treatment, and nearby enlarged lymph nodes. Diagnosis requires a deep biopsy and imaging; treatment often involves wide surgical excision, possible lymph node assessment, and sometimes amputation or adjunct radiation.

Prevention and vigilance are crucial: optimize diabetes and vascular care, monitor chronic wounds closely, and refer promptly for suspicious changes. Emerging research on biomarkers, targeted therapies, and AI imaging aims to detect malignant transformation earlier.

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Avsnitt(373)

Forgotten Infection Friday: The Fishy Case of Erysipelothrix

Forgotten Infection Friday: The Fishy Case of Erysipelothrix

This episode explains Erysipelothrix rhusiopathiae, an animal-associated bacterium that can enter through minor skin breaks—often from fish, meat, or livestock exposure—and cause a localized lesion ca...

5 Sep 41min

When a Toe Is More Than Tissue: The Ethics of Diabetic Foot Consent

When a Toe Is More Than Tissue: The Ethics of Diabetic Foot Consent

Dr. G explains why informed consent in diabetic foot care is more than paperwork: it’s a time-sensitive conversation about capacity, risks, alternatives, and what happens if treatment is delayed. The ...

3 Sep 18min

Applying Newton’s Laws to Diabetic Foot Ulcers

Applying Newton’s Laws to Diabetic Foot Ulcers

In this episode Dr. G explains how Newton’s laws of motion illuminate why some diabetic foot ulcers heal and others recur. He connects concepts like force, pressure, shear, and ground reaction forces ...

2 Sep 41min

LIMBWatch Series: Dr. Jared Adams MD,PhD : Your Story Could Save a Limb: Inside the New Diabetic Foot Ulcer Patient Registry STEADY

LIMBWatch Series: Dr. Jared Adams MD,PhD : Your Story Could Save a Limb: Inside the New Diabetic Foot Ulcer Patient Registry STEADY

Your Story Could Save a Limb: Inside the New Diabetic Foot Ulcer Patient Registry What if the most important piece of diabetic foot ulcer research isn’t another clinical endpoint—but the patient’s sto...

31 Aug 49min

LIMBWatch Series: Dr. Sukoff, Dr. Hanley & Dr. Warren -     LIMBWatch: From Chronic Wound to Limb Preservation — The Science Behind Lavior

LIMBWatch Series: Dr. Sukoff, Dr. Hanley & Dr. Warren - LIMBWatch: From Chronic Wound to Limb Preservation — The Science Behind Lavior

Episode Summary In this episode of LIMBWatch, we go beyond the wound itself to explore the science, clinical challenges, and innovations shaping the future of limb preservation. We are joined by the t...

24 Aug 41min

Copper: A  Surprising Possible Ally in Diabetic Foot Ulcer Healing

Copper: A Surprising Possible Ally in Diabetic Foot Ulcer Healing

In this episode of Diabetic Fit Files Dr. G explores how the trace element copper affects diabetic foot ulcers at the cellular and molecular level. Topics include copper's roles in angiogenesis, colla...

23 Aug 27min

Reflexes, Tuning Forks & Monofilaments: Inside the Diabetic Foot Exam

Reflexes, Tuning Forks & Monofilaments: Inside the Diabetic Foot Exam

This episode breaks down the neurological exam of the diabetic foot, explaining reflexes, vibration testing, monofilament assessment, proprioception, pinprick and temperature testing, and the autonomi...

22 Aug 27min

“I Have a Diabetic Foot Ulcer… But I Don’t Have Insurance. Now What?”

“I Have a Diabetic Foot Ulcer… But I Don’t Have Insurance. Now What?”

This episode explains what to do if you have a diabetic foot ulcer and no health insurance, stressing that you should not ignore the wound or try to self-treat. It covers signs of infection, the need ...

21 Aug 17min

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