
Ep 88: Negative Adjuvant Doublet Studies (CM915, KV010, RELA098)
Melanoma Matters: Why Adjuvant Doublet Immunotherapy Fell ShortHobbies - James wishes he was surfing more This episode breaks down three negative adjuvant melanoma trials testing combination immunothe...
1 Sep 22min

Ep 86: Teaser Tudriqev (RP1) FDA Approval
James asks the big question
25 Aug 10s

Ep 87: INTerpath-001 Press Release - August 2026
In this episode, Sapna and James discuss the INTerpath-001 press release describing primary endpoint (RFS) and key secondary endpoint (DMFS) findings from the randomized phase 3 study of individualize...
25 Aug 12min

Ep 85: Surgical considerations for TIL
In this episode, Sapna and James talk tv shows - The Gambler and His Cowboys, Brassic... They discuss the paper from NKI on surgical considerations for TIL harvest published in BJS in 2025. Topics of ...
28 Juli 29min

Ep 84: Merlin CP-GEP and Castle i31-SLNB tests
In this episode, the chin dimple is front and center. James explains the wizarding home of Tintagel in Cornwall to Sapna, situated on a lovely promontory. This episode explores the latest evidence on ...
24 Juli 35min

Ep 83: Guest Megan Othus and Time of Day Administration
James and Sapna welcome Megan Othus, Professor of Biostatistics at the Fred Hutch Cancer Center and one of the key statisticians at SWOG.Megan talks about growing up in the PNW and going East to get b...
24 Juni 40min

Ep 82: Best of ASCO: 2026
In this episode, James & Sapna tease the size of ASCO and ESMO and number of simultaneous publications.They review the most impactful melanoma and Merkel cell carcinoma presentations from ASCO 2026, f...
13 Juni 1h 4min




















