Does EmbryoGlue Really Improve IVF Success? New ESHRE Research Challenges a Popular IVF Add-On

Embryo Glue is one of the most talked-about IVF add-ons. Does it actually lives up to the hype?

I invited Dr. Nirvika Singh Sharma, associate lab director at Ovation Fertility San Antonio, to share what her new research found about embryo glue.

Dr. Sharma is a physician, reproductive scientist, and embryologist who recently led a major study presented at ESHRE examining whether EmbryoGlue, a high-concentration hyaluronan transfer medium, actually improves outcomes in frozen embryo transfer cycles. We dig into what embryo glue really is, what her research found across 593 euploid FET cycles, and what patients should know before paying extra for this popular IVF add-on.

Read the full show notes.

In this episode, we cover:

What EmbryoGlue actually is
How hyaluronan works in the reproductive tract and whether more of it helps implantation
Dr. Sharma's study design: 593 single euploid frozen embryo transfers across four medium combinations
The results: pregnancy rates were 63–67% regardless of whether EmbryoGlue or standard media was used
The difference between proven effective and possible benefit in IVF add-ons
What actually drives implantation: embryo quality, ploidy, and the embryo-endometrium conversation

Resources:

Ovation Fertility San Antonio: ovationfertility.com
Connect with Dr. Nirvika Singh Sharma on LinkedIn
Dr. Sharma's research presented at ESHRE (European Society of Human Reproduction and Embryology)

Do you have questions about IVF?
Click here to join Dr. Aimee for The IVF Class.

The next live class call is on Monday, October 19 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.

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Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

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