When AI and Genomics Collide
a16z Podcast3 Okt 2023

When AI and Genomics Collide

Today’s episode continues our coverage from a16z’s recent AI Revolution event. You’ll hear a16z Bio & Health GP Vijay Pande speak with Daphne Koller about the fascinating convergence of machine learning and genomics – two industries that have benefitted decades of investment and progress – which are now colliding head on.

Daphne is a prominent innovator at this intersection, as a long-time professor in computer science at Stanford and co-founder of Coursera, who has decided to step back into the arena with her company Insitro. In fact, Insitro is a blend of in silico and in virto!

If you’d like to access all the talks from AI Revolution in full, visit a16z.com/airevolution.

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Subscribe on your favorite podcast app: https://a16z.simplecast.com/

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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How Fintech is Reshaping Our $4T Healthcare Industry

How Fintech is Reshaping Our $4T Healthcare Industry

In this episode, you’ll hear directly from 6 founders trying to reinvent the healthcare system with the help of Fintech.They’re tackling everything from the lack of price transparency, the complexity of billing, getting clinics paid on time, mental health support for the masses, virtual first-care, and the millions of Americans about to lose access to Medicaid. Topics Covered:00:00 - The biggest problems in healthcare02:22 - The lack of price transparency07:13 - The complexity of medical billing14:32 - Getting health clinics paid on time20:00 - Mental health support for the masses24:58 - Millions about to lose Medicaid29:12 - Adopting virtual-first careResources:Learn more about the intersection of Healthcare and Fintech: https://a16z.com/healthcare-meets-fintech/Check out Turquoise: https://turquoise.health/Check out Cedar: https://www.cedar.com/Check out Camber Health: http://camber.health/Check out Headway: https://headway.co/Check out Propel: https://www.joinpropel.com/Check out Firefly: https://www.firefly.health/Find Chris on Twitter: https://twitter.com/crsevern?lang=enFind Florian on Twitter: https://twitter.com/flottobrasil?lang=enFind Jade on Linkedin: https://www.linkedin.com/in/jadeyychan/Find Andrew on Twitter: https://twitter.com/andrewlangadams?lang=enFind Jimmy on Twitter: https://twitter.com/jimmychen?lang=enFind Fay on Twitter: https://twitter.com/fyietc Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

22 Maj 202337min

Embedding AI: The Questions Every CEO is Asking

Embedding AI: The Questions Every CEO is Asking

2022 was a breakout year for AI. While machine learning had already been integrated into applications for millions of users, for many, these tools still felt like their first real-world encounter with AI.As AI continues to revolutionize industries, CEOs are discussing how to integrate this new superpower. They are also considering important questions around data privacy, competition, cost, accuracy, and speed.In today's episode, we talk with Cresta, Hex, and Sourcegraph, three companies at the forefront of integrating AI into their existing products. From navigating data privacy concerns to optimizing accuracy and managing costs, these leaders are navigating the complexities of this new superpower.Topics Covered:00:00 - Introduction02:51 - How AI can enhance customer service08:26 - Using AI to shape data and analytics09:33 - Solving the challenges on contextual understanding12:01 - Giving AI the right information and context13:31 - Tools that help build language Models (LLMs)15:39 - Building open source tools18:40 - Constructing prompts22:26 - How do you differentiate?23:48 - Customization as a moat25:26 - Privacy challenges29:14 - Language models and search engines30:41 - Cost and pricing of models32:48 - What does the contact center look like in 2028?Resources:Find Barry McCardel on Twitter https://twitter.com/barraldFind Beyang Liu on Twitter: https://twitter.com/beyangFind Zayd Enam on Twitter: https://twitter.com/zaydenamRecent AI episodes:From Promise to Reality: Inside a16z's Data and AI ForumBeyond Avatars: How AI is Reshaping Online IdentityUnlocking Creativity with Prompt EngineeringStay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see

15 Maj 202336min

When Two Giants Intersect: Healthcare Meets Fintech

When Two Giants Intersect: Healthcare Meets Fintech

Most people don’t need a reminder of the state of healthcare in America. But it’s not just the consumer that’s hurting.  Medical debt is increasing, billions are lost in unpaid claims, hospitals are in the red, service prices can range up to 30x…. In this episode, a16z GPs Julie You and David Haber explain where the healthcare system breaks down and how the three party system — between payors, providers, and consumers — can be rethought through the lens of Fintech.Learn more about Healthcare x Fintech here: https://a16z.com/healthcare-meets-fintech/Topics Covered:00:00 - Introduction02:50 - The intersection of healthcare and fintech 05:40 - The problems within US healthcare 09:00 - The stats behind US healthcare12:10 - Where do the problems stem from in healthcare?15:50 - New opportunities and regulatory changes17:50 - Pushback on regulations19:40 - Provider and patient models and transparency21.10 -  The ‘No Surprises Act’ and the ‘Cures Act’23:20 - Applying fintech infrastructure to healthcare26:00 - Example: how Juniper in embedding fintech in healthcare30:10 - Opportunities in the healthcare/fintech market33:05 - Payvidors unbundled 34:55 - The financial operating system for healthcare37:40 - How founders can approach the problems39:23 - The investor standpoint on company opportunities41:00 - Unsolved problems in the market45:25 - The bridge between start-ups and incumbents 47:20 - Healthcare incumbent stats  48:50 - The window of opportunity for healthcare and fintechResources:Read the article ‘Healthtech x Fintech’s Biggest Prize: The Financial Operating System for Healthcare: https://a16z.com/2023/02/07/healthtech-x-fintechs-biggest-prize/Read the article ‘ Payvidors, Unbundled: Opportunities in Healthcare Fintech’:https://a16z.com/2022/06/01/payvidors-unbundled-opportunities-in-healthcare-fintech/Find Julie on Twitter :https://twitter.com/julesyooFind David on Twitter: https://twitter.com/dhaberStay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

9 Maj 202349min

From Promise to Reality: Inside a16z's Data and AI Forum

From Promise to Reality: Inside a16z's Data and AI Forum

Nvidia’s CEO Jensen Huang declared in a recent keynote, “we are in the iPhone moment of AI.”This special episode will give you an inside look into a16z’s Data and AI Forum, hosted the day GPT-4 came out, featuring many of the most influential builders in the space – from the companies building foundational models like OpenAI to those building the underlying infrastructure like AWS. Resources:Check out CoactiveAI: https://coactive.ai/Check out CharacterAI: http://character.ai/Check out Hex: https://hex.tech/Follow Cody on Twitter: https://twitter.com/codyaustunFollow Myle on Twitter: https://twitter.com/myleottFollow Barry on Twitter: https://twitter.com/barrald Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

2 Maj 202327min

Beyond Avatars: How AI is Reshaping Online Identity

Beyond Avatars: How AI is Reshaping Online Identity

In a recent episode, we delved into the first wave of technology that was used to create digital influencers like 'Lil Miquela back in 2016.Fast forward to today, we're presented with a whole new set of tools that enable almost anyone to build their own digital influencer. In this episode, Sinead Bovell and Danny Postma discuss the transformative impact of artificial intelligence on the world of modeling, online creation, and self-representation.From the rise of AI-generated photos to the democratization of creativity, they discuss the potential of AI in shaping the future of digital expression.Topics Covered:00:00 - Introduction03:08 - The key insight08:00 - The photo studio of the future09:44 - Programs and models behind deep fakes10:58 - How the technology is used today12:36 - How real is today’s content?15:29 - The cost of a virtual model17:13 - Industry benefits19:28 - Market appetite23:25 - Evolving tech25:15 - Unlocking a new wave of creativity28:38 - Future predictions30:23 - Keeping up with tech32:02 - Finding a moat34:09 - Stacked AI models35:25 - Running your own GPUs and models37:33 - Product ideasResources:Find Danny Postma on Twitter: https://twitter.com/dannypostmaaHeadshot Pro, ProfilePicture.Ai plus all of Danny’s projects at: https://www.postcrafts.com/Find Sinéad Bovell on Instagram: https://www.instagram.com/sineadbovell/?hl=en Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

24 Apr 202339min

Insights from the Frontlines of Consumer Tech

Insights from the Frontlines of Consumer Tech

There is arguably nothing that impacts our daily lives more than consumer technology. This technology can drive our ability to change careers, build an audience, or feel understood. And in this episode, listeners get a sneak peek into our new consumer series, Field Notes, where a16z’s very own Connie Chan speaks with the builders, creators, and investors behind the technology that shapes our daily lives.If you like these segments, you can find the full episodes at a16z.com/fieldnotes.Topics Covered:00:00 - Introduction02:13 - Chris Schroder08:15 - Brian Wong15:35 - Tracy Sun23:03 - Deb Liu30:56 - Susan PlagemannResources: Find the full series: https://a16z.com/fieldnotesFind Connie on Twitter: https://twitter.com/conniechanDeb's Part 1:  https://www.youtube.com/watch?v=Is2pm06MNt8Deb's Part 2: https://www.youtube.com/watch?v=osJp6S66u2UChris's episode: https://www.youtube.com/watch?v=Zux1wVirUjs Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

19 Apr 202335min

Marketing web3: Audience, Community, More

Marketing web3: Audience, Community, More

with @amandacassatt @kimbatronic @smc90All about marketing, and web3 -- not just for marketers already in or seeking to enter web3, but also anyone doing community marketing/ community management, devrel (developer relations); or simply doing marketing in web2 or classic growth marketing, seeking to understand the latest trends and tactics.With the  author of the new book, Web3 Marketing: A Handbook for the Next Internet Revolution, Amanda Cassatt (who was also the first CMO at ConsenSys, helping bring Ethereum to market; and also founded and leads the pioneering, native web3-marketing agency Serotonin). Also joining this episode to share insights on marketing web3 -- in conversation with host and editor in chief Sonal Chokshi -- is Kim Milosevich, CMO at a16z crypto, where she oversees brand, marketing, events, and communications (and before that was VP of communications at Coinbase, where she took the company through its direct listing while leading internal, policy, product, and corporate communications internationally). The episode also covers key top of mind questions for web3 builders and others, including how to do community marketing, manage "profiles" in decentralized and open source, and finding your audience... including feedback for product-market fit. And much. much more!

13 Apr 20231h 16min

Building Hardware and Taking on the Phone Giants

Building Hardware and Taking on the Phone Giants

People often say that building a hardware company is like “playing on hard mode”. Building a hardware company during a global pandemic, with the unpredictability of supply chains and markets, is harder than hard. Trying to penetrate the phone market in particular – where only a few players own almost all the market share – is REALLY hard.In today’s episode we chat with Carl Pei, founder of Nothing. Between Nothing and previously co-founding OnePlus, Carl has twice managed to do what many others have failed to do. Nothing has sold over 1m units and built a team of over 400. In this episode, Carl chats with us about why he’s at it again, what it takes to successfully build hardware, and how he thinks about making technology fun again.Timestamps:02:11 - The hardware market02:53 - Breaking into the phone market05:19 - Securing factories and stakeholders07:39 - Differentiating products10:32 - Hardware design11:53 - Strengthening software proposition16:04 - Table stakes17:49 - Marketing and Youtube19:34 - Underestimating the value chain21:50 - Manufacturing23:27 - Supply chain26:05 - Remote work27:36 - The future of hardware30:45 - Breakthrough hardware32:35 - Making tech fun againResources:Nothing website: https://us.nothing.tech/Nothing’s Youtube channel: https://www.youtube.com/@NothingTechnologyFind Carl on Twitter: https://twitter.com/getpeidFind Nothing on Twitter: https://twitter.com/nothingNothing’s recently launched Ear (2): https://us.nothing.tech/products/ear-2Stay Updated: Find a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

6 Apr 202337min

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