Orphan Drugs
99% Invisible14 Nov 2018

Orphan Drugs

We chronicle the epic struggle to get drugs that treat very rare diseases on the market, and the unintended consequence of that fight, which affected the cost of all kinds of drugs. This is a strange story that involves a hit 70s TV show, a fake march on Washington, a courageous advocate, a carnival concessions wholesaler, and a new drug law that helped a lot of people, made drug companies billions of dollars, and opened a whole can of worms.

Adapted from the new podcast An Arm and a Leg by Dan Weissmann

Orphan Drugs

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Edge of Your Seat

Edge of Your Seat

“A Chair is a difficult object. A skyscraper is almost easier.” — Mies van der Rohe. The chair presents an interesting design challenge, because it is an object that disappears when in use. The person replaces the chair. So chairs need to … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

4 Nov 201414min

O-U-I-J-A

O-U-I-J-A

The Ouija board is so simple and iconic that it looks like it comes from another time, or maybe another realm. The game is not as ancient as it was designed to look, but those two arched rows of letters have … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

28 Okt 201417min

Good Bread

Good Bread

The first print advertisement for Wonder Bread came out before the bread itself. It stated only that “a wonder” was coming. In a lot of ways, the statement was true. Wonder Bread was the perfect loaf.  “Slow food” advocates have pronounced industrial … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

22 Okt 201415min

Kickstart Radiotopia- A Storytelling Revolution

Kickstart Radiotopia- A Storytelling Revolution

When you support Radiotopia, you are making sure 99% Invisible can keep coming to you weekly and you’ll be supporting our entire collective of award-winning, independent radiomakers. Thanks!   Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

19 Okt 20142min

Lights Out

Lights Out

On July 13th, 1977, lightning struck an electricity transmission line in New York City, causing the line’s automatic circuit breaker to kick in. The electricity from the affected line was diverted to another line. This was fairly normal and everything … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

14 Okt 201414min

For Amusement Only

For Amusement Only

Everyone has tried it at some point. The authorities started turning a blind eye years ago, but it wasn’t officially legalized until the summer of 2014. Finally, after more than 80 years of illegitimacy, the City of Oakland has legalized…pinball … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

7 Okt 201413min

The Straight Line Is A Godless Line

The Straight Line Is A Godless Line

Straight lines form the core of our built environment. Building in straight lines makes predicting costs and calculating structural loads easier, since building materials come in linear units. Straight lines might be logical, predictable, and efficient, but they are also … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

30 Sep 201415min

Port of Dallas

Port of Dallas

There’s a photograph we have tacked to our studio at 99% Invisible HQ. The photo, taken 1899, shows three men, all looking very fashionable, suspended mid-air on the lifted arm of a giant dredging machine. There are plenty of images … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

24 Sep 201417min

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