Orphan Drugs
99% Invisible14 Nov 2018

Orphan Drugs

We chronicle the epic struggle to get drugs that treat very rare diseases on the market, and the unintended consequence of that fight, which affected the cost of all kinds of drugs. This is a strange story that involves a hit 70s TV show, a fake march on Washington, a courageous advocate, a carnival concessions wholesaler, and a new drug law that helped a lot of people, made drug companies billions of dollars, and opened a whole can of worms.

Adapted from the new podcast An Arm and a Leg by Dan Weissmann

Orphan Drugs

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The Best Beer in the World

The Best Beer in the World

If you’re a beer nerd, or have a friend who’s a beer nerd, you’ve heard of Belgian beers. Belgians take beer very seriously. Amongst the 200 Belgian breweries, there’s a very specific sub-type: Trappist beers. According to our reporter Cyrus … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

31 Maj 201213min

The Colour of Money

The Colour of Money

US paper currency is so ubiquitous that to really look at its graphic design with fresh eyes requires some deliberate and focused attention. So pull out a greenback from your wallet (or look at a picture one online) and just … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

16 Maj 201217min

The Xanadu Effect

The Xanadu Effect

What happens when we build big? Julia Barton remembers going to the top floor of Dallas’s then-new city hall when she was teenager. The building, designed by I.M. Pei, is a huge trapezoid jutting out over a wide plaza. Julia … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

1 Maj 201211min

Galloping Gertie

Galloping Gertie

Even during the construction of the original Tacoma Narrows Bridge, the deck would go up and down by several feet with the slightest breeze. Construction workers on the span chewed on lemon wedges to stop their motion sickness. They nicknamed … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

18 Apr 201212min

The Arsenal of Exclusion

The Arsenal of Exclusion

“Cities exist to bring people together, but cities can also keep people apart” – Daniel D’Oca, Urban Planner, Interboro Partners. Cities are great. They have movement, activity and diversity. But go to any city and it’s pretty clear, a place … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

3 Apr 201211min

DeafSpace

DeafSpace

The acoustics of a building are a big concern for architects. But for designers at Gallaudet University in Washington, DC, it’s the absence of sound that defines the approach to architecture. Gallaudet is a university dedicated to educating the deaf … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

22 Mars 201212min

Queue Theory and Design

Queue Theory and Design

In the US, it’s called a line. In Canada, it’s often referred to as a line-up. Pretty much everywhere else, it’s known as a queue. My friend Benjamen Walker is obsessed with queues. He keeps sending me YouTube clips of … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

9 Mars 201210min

The Bathtubs or the Boiler Room

The Bathtubs or the Boiler Room

“I have this habit of walking into any door that’s unlocked…You start poking around, going into doors…you find the coolest things…” -Andrea Seabrook, NPR Congressional Correspondent In the eight years Andrea Seabrook has been reporting on Congress, she has made … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

26 Feb 201211min

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