Is high cholesterol always a problem? | Nick Norwitz, PhD

Is high cholesterol always a problem? | Nick Norwitz, PhD

Episode #323. Oreo cookies or statins – which is more effective in reducing LDL cholesterol? The results from one study might surprise you. Join me as I sit down with Oxford PhD graduate and Harvard Medical student Dr Nick Norwitz to discuss the lipid energy model, what it has to do with Oreos, and how different diets affect your health. You’ll learn about Dr Norwtiz’s health journey, including his experience with inflammatory bowel disease and the ketogenic diet. We discuss cholesterol management and cardiovascular disease risk, lean mass hyper-responders, and statins. This episode is an important and informative reflection on scientific curiosity and misinformation. Specifically, we discuss: Introduction (00:00:00) The Importance of Curiosity in Scientific Progress (04:39) Exploring the Oreo vs. Statin Experiment on Lean Mass Hyper Responders (08:52) Scientific and Clinical Impact of the Oreo Study (25:03) Addressing Criticisms and Misinterpretations of the Study (34:47) Navigating Statin Discussions on Social Media (40:27) Debunking Claims About PCSK9 Inhibitors (53:18) Challenging Misinformation in Health Communities (59:15) The Lipid Energy Model and Lean Mass Hyper Responders Explained (01:06:59) Defining Lean Mass Hyper Responders: Key Terminology (01:14:19) Practical Advice for Lean Mass Hyper Responders (01:30:35) The Carnivore Kid: An Intriguing Case Study (01:41:48) Personal Struggles with Ulcerative Colitis and Starting Keto (01:45:24) Balancing Medication and Personal Health Choices (01:50:31) Debating Dietary Interventions for Inflammatory Bowel Disease (02:11:09) Challenges in Dietary Research and Medical Interventions (02:25:55) Introducing the Lipid Energy Model and Its Mechanisms (02:34:49) Debating the Validity of the Lipid Energy Model (02:44:29) Long-Term Effects of Ketosis and Carb Restriction (02:52:31) Critiques and Limitations of the Lipid Energy Model (02:57:17) ApoB-Containing Lipoproteins and Atherosclerosis (03:03:50) Current Research and Future Directions on LMHR (03:06:41) Exploring Inflammatory Responses to Fibre (03:16:12) The Link Between Saturated Fats and Heart Disease (03:20:49) Closing Thoughts on Effective Scientific Communication (03:25:29) The Lean Mass Hyper Responders Debate: Addressing Frustrations (03:32:32) Understanding Carbohydrate Reintroduction Physiology (03:46:58) Diet-Specific Strategies to Lower ApoB (03:55:16) Examining Claims About ApoB and Cardiovascular Disease (04:01:50) Trade-offs in Lowering ApoB Levels (04:12:54) Exploring the Link Between All-Cause Mortality and ApoB (04:22:42) Lean Mass Hyper Responders and ApoB: A Unique Profile (04:44:54) Concluding Thoughts and Future Discussion Topics (04:48:10) Connect with Nick Norwitz, PhD on Twitter/X, Instagram, and YouTube. Make sure to check out the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(429)

Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado

Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado

Everyone wants to talk about longevity. Almost no one wants to talk about gerontology, the field that has been studying how to age well for a century. Dr Deborah Kado, Stanford professor of medicine a...

31 Aug 1h 35min

Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor

Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor

Professor Roy Taylor returns, three years after his first appearance, with the five-year DiRECT trial results and a clear-eyed assessment of where diet-driven type 2 diabetes remission stands in the G...

25 Aug 1h 24min

Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess

Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess

Can you meaningfully improve type 2 diabetes without losing weight? Dr Nicola Guess, registered dietitian and Senior Research Fellow at the University of Oxford, says the evidence is clear: a higher-p...

17 Aug 1h 8min

The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford

The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford

About one in seven couples are unable to conceive after a year of trying, and roughly half of those cases involve a male contribution. Yet in a quarter to a third of them, the man is never properly ev...

10 Aug 2h 3min

Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson

Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson

Dr Terry Simpson is back, and we go deep on the science of protecting your heart and brain for the long run. He is a surgeon and one of the clearest voices online for separating solid evidence from co...

4 Aug 1h 53min

The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass

The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass

Metabolic dysfunction rarely announces itself. We tend to think of metabolic health as a line you cross the day you are diagnosed with type 2 diabetes, but the decay usually begins years earlier, at t...

27 Juli 2h 20min

New Science of Weight Loss | A Masterclass

New Science of Weight Loss | A Masterclass

GLP-1 medications are transforming obesity treatment, but they're only one piece of the puzzle. In this masterclass, I bring together insights from Dr Terry Simpson, Dr Federica Amati, Dr Mauricio Gon...

20 Juli 1h 54min

Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati

Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati

We tend to treat pregnancy as the starting line for a child's health. In this episode, Dr Federica Amati, Head Nutritionist at ZOE, makes the evidence-based case that the window opens earlier, in the ...

13 Juli 1h 23min

Populärt inom Utbildning

historiepodden-se
det-skaver
rss-bara-en-till-om-beroende-medberoende
harrisons-dramatiska-historia
nu-blir-det-historia
roda-vita-rosen
rss-viktmedicinpodden
rikatillsammans-om-privatekonomi-rikedom-i-livet
johannes-hansen-podcast
allt-du-velat-veta
i-vantan-pa-katastrofen
not-fanny-anymore
rss-max-tant-med-max-villman
sa-in-i-sjalen
rss-ar-det-rimligt
rss-foraldramotet-bring-lagercrantz
rss-basta-livet
sektledare
rss-traningsklubben
rss-autismandan