Grand Challenges in Healthcare AI

Don Faul, head of operations at Pinterest and a former U.S. Marine Corps Platoon Commander, grills Marc Andreessen in front of a crowd of veterans at an event we hosted for bringing more veterans into startups. The discussion ranges from what makes great founders great; the shift to venture capital; and how Silicon Valley is all about “applied creativity.” All that, plus the three books every entrepreneur should read...

11 Nov 201443min

It’s always hard to predict how a generational shift in technology will impact the wider world, especially when you are in the trenches building that new technology. It happened with the mainframe computer, mini-computer, and the PC. These were all technologies that fundamentally changed how industries functioned and culture evolved (especially the PC plus internet), and in ways that were hard to predict. With mobile and the smartphone, a16z’s Benedict Evans argues, the impact will be even greater. a16z Board Partner Steven Sinofsky joins Evans in a conversation examining the massive scale and monstrous leverage of mobile devices and the software running on them and how -- unpredictably as always -- this technological shift is changing the world. As Sinofsky puts it, “Mobile is everything.” The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

31 Okt 201422min

It’s well understood that bitcoin can be used to buy and sell things/services, and the ecosystem of people accepting the cryptocurrency as payment is expanding. But what else can we use the underlying protocol for? How can we expand the same system that enables bitcoin-the-currency to flow and transactions to be recorded? This discussion (from the a16z Academic Roundtable 2014) examines that question, and answers why the currency is just the beginning of the story when it comes to this technology. You can watch video of the entire discussion here: http://a16z.com/2014/10/24/the-bitcoin-network-effect/ The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

24 Okt 201429min

What is Silicon Valley’s greatest reigning monopoly? How did PayPal manage to emerge from the dotcom implosion? Can you build a great tech company and keep it private forever? And how did Elon Musk manage to wreck an uninsured, million-dollar car with Peter Thiel in the passenger seat speeding on the way to a VC meeting? Marc Andreessen and Thiel discuss all of it in a wide-ranging conversation that toggles off the topics in Thiel’s new book “Zero to One.”

17 Okt 201446min

It's a myth that startups happen in isolation. Those legendary two people in a garage are often building on the deep and basic research -- long funded by government and conducted in universities -- that has come before it. But with the advent of the internet, what's the future of peer-to-peer collaborations and startups-as-"science experiments"? Can venture capital disrupt academia… and vice versa? And finally, what's the secret to universities like Stanford making money off the entrepreneurial ideas coming out of them? (Hint: It starts with a 'p'. But not what you think.) a16z's new professor in residence Vijay Pande interviews Marc Andreessen at our recent Academic summit on these topics, as well as 'regulatory arbitrage', how to mix humanities and science, and what Marc would have majored in if he were 18 today.

2 Okt 201423min

Jonah Peretti is building BuzzFeed to “inform, inspire and entertain” in a world where news and entertainment is increasingly passed around on social networks and consumed on smartphones. Chris Dixon, who is on the board of BuzzFeed as part of Andreessen Horowitz’s recent investment in the startup, sat down with Peretti to talk about building a media company from scratch. If editorial success is driven by digital word-of-mouth, and mountains of data about what people like to read and watch, what does Peretti do differently? Why do BuzzFeed’s lists work so well? Does video finally make financial sense? And why, even if it’s a traffic monster now, is Peretti not religious about any particular format -- including lists. (For more on Dixon’s take on the media business, and BuzzFeed’s “full stack” approach check out this recent post: http://cdixon.org/2014/08/10/buzzfeed/) The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

18 Sep 201426min

Software, and the billions of transistors that power it, has brought about massive change to all kinds of industries, but none more so than the news business. Today, distribution doesn’t come from the back of trucks, but from Facebook, Twitter and all across the social web. Relationships with readers and viewers have become a two-way conversation. It’s not news that the traditional business model of news has come under extreme pressure, but there is growing evidence that the reach of media outlets -- and in many ways the opportunity -- has never been greater. In today’s unending news cycle, the latest story, video or graphic is only a tap away from a potential audience of billions around the world. Andreessen Horowitz’s Margit Wennmachers leads a conversation about the road ahead for good journalism and the business of news with Claire Cain Miller from the New York Times, Alexis Madrigal from The Atlantic, and CNET’s Connie Guglielmo.

17 Sep 201435min

Nir Eyal and Product Hunt's Ryan Hoover, the authors of "Hooked, How to Build Habit-Forming Products," discuss the theory and practice of the book as the publish date of a new edition approaches. Nir lays out the four steps integral to any habit-forming product -- trigger, action, reward, investment -- and Ryan describes how those same steps apply to the fast-growing Product Hunt. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

15 Sep 201420min