a16z Podcast: Beyond Lean Startups

Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How fun, challenging, and fulfilling would it have been to work on semiconductors in the 1950s or Unix in the 1960s (both at Bell Labs) or personal computers at the Homebrew Computer Club in the 1970s or on the Internet browser at the University of Illinois at Urbana-Champaign (and later Mountain View, CA) in the 1990s? Good news: it’s not too late. There’s a new computing platform being built today by a vibrant and rapidly growing cryptocurrency community. You might have noticed some of your coworkers and friends leaving big stable tech companies to join crypto startups. In this episode, which originally appeared on YouTube, a16z crypto partner Ali Yahya (@ali01) talks with Frank Chen (@withfries2) about five challenging problems the community is trying to solve right now to enable a new computing platform and a new set of killer apps: *Scaling decentralized computing *Scaling decentralized storage *Scaling decentralized networks *Establishing trusted identities and reputation *Establishing trusted governance models If you’re a software engineer, product manager, UX designer, investor, or tech enthusiast who thrives on the particular challenges of building a new computing platform, this is the perfect time to join the crypto community. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

13 Maj 201952min

with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread) Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will breastfeeding babies make them smarter? There’s maybe no other arena where understanding what the evidence truly tells us is harder than in health… and parenting. And yet we make decisions based on what we hear about in studies like the ones listed above every day. In this episode, Brown University economics professor Emily Oster, author of Expecting Better and the recently released book Cribsheet: A Data-driven Guide to Better, More Relaxed Parenting, from Birth to Preschool, in conversation with Hanne Tidnam, dives into what lies beneath those studies... and how to make smarter decisions based on them (or not). Oster walks us through the science and the data behind the studies we hear about -- especially those hot-button parenting issues that are murkiest of all, from screen time to sleep training. How we can tell what’s real and what’s not? Oster shows us the research about how these guidelines and advice that we are "supposed" to follow get formalized and accepted inside and outside of healthcare settings -- from obstetrics practices to pediatrics to diet and lifestyle; how they can (or can’t) be changed; and finally, how the course of science itself can be influenced by how these studies are done.

11 Maj 201941min

with @annieduke, @pmarca, and @smc90 Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or others -- makes countless decisions every day, under conditions of uncertainty. The question is, are we allowing that uncertainty to bubble to the surface, and if so, how much and when? Where does consensus, transparency, forecasting, backcasting, pre-mortems, and heck, even regret, usefully come in?Going beyond the typical discussion of focusing on process vs. outcomes and probabilistic thinking, this episode of the a16z Podcast features Thinking in Bets author Annie Duke -- one of the top poker players in the world (and World Series of Poker champ), former psychology PhD, and founder of national decision education movement How I Decide -- in conversation with Marc Andreessen and Sonal Chokshi. The episode covers everything from the role of narrative -- hagiography or takedown? -- to fighting (or embracing) evolution. How do we go from the bottom of the summit to the top of the summit to the entire landscape... and up, down, and opposite?The first step to understanding what really slows innovation down is understanding good decision-making -- because we have conflicting interests, and are sometimes even competing against future versions of ourselves (or of our organizations). And there's a set of possible futures that result from not making a decision as well. So why feel both pessimistic AND optimistic about all this??

8 Maj 201946min

In a followup to one of our most popular podcast episodes which originally aired in April 2017 (https://a16z.com/2017/04/03/cryptocurrencies-protocols-appcoins/), a16z Crypto Fund General Partner Chris Dixon returns to talk with Olaf Carlson-Wee of Polychain Capital in a free-wheeling conversation about the seven major trends they see happening in blockchain computing now as we shift from basic protocol design to pragmatic product launches: Improving developer productivity Scaling out versus scaling up On-chain governance Proof of Stake Networks, and especially their resilience to attacks 2017: year of of fund raising, 2019: year of launches Autonomous and re-mixable code Killer apps: distributed finance and beyond This conversation was originally recorded for our YouTube channel: https://www.youtube.com/c/a16zvideos The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see a16z.com/disclosures for additional important information.

7 Maj 201950min

As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automated. This creates opportunities for startups creating new ways to collect and analyze data to support this new style of decision making. In this episode (which originally aired as a YouTube video), Jad Naous (@jadtnaous) ‏and Frank Chen (@withfries2) discuss this change and the startup opportunities these changes create. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see a16z.com/disclosures for additional important information.

29 Apr 201929min

with Jorge Conde (@JorgeCondeBio), Julie Yoo (@julesyoo), and Hanne Tidnam (@omnivorousread) Building a software company in healthcare is hard -- and comes along with unique challenges no other entrepreneurs face. In this conversation, a16z bio general partner -- and previous founder of genomics company Knome -- Jorge Conde; and a16z bio partner and former founder Julie Yoo (of patient provider matching system, Kyruus) share their mistakes and hard earned lessons learned with a16z partner Hanne Tidnam. Why is this so damn hard? How should founders think about this space differently? What are the specific things that healthcare founders can do -- when, where, and why? You'll wish you only knew this when you started your own company!

25 Apr 201936min

Join longtime Apple software engineer Ken Kocienda in conversation with a16z Deal and Research operating partner Frank Chen for an insider’s account of how Apple designed software in the golden age of Steve Jobs, spanning products like the first release of Safari on MacOS to the first few releases of the iPhone and iOS (very first codename: "Purple"). Ken vividly shares about the creative process, how teams were organized, what it was like demo'ing to Steve Jobs, and many other fun stories. This episode originally aired as a YouTube video, and throughout, we repeatedly probe the question: is Apple's obsession with secrecy during the product development process a feature or a bug?

19 Apr 20191h 36min

In this episode of the a16z Podcast -- which originally aired as a video on YouTube -- general partner Alex Rampell (and former fintech entrepreneur as the CEO and co-founder of TrialPay) talks with operating partner Frank Chen about the quickly changing fintech landscape and, even more importantly, why the landscape is changing now. Should the incumbents be nervous? About what, exactly? And most importantly, what should big companies do about all of this change? But the conversation from both sides of the table begins from the perspective of the hungry and fast fintech startup sharing lessons learned, and then moves to more concrete advice for the execs in the hot seat at established companies. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.) Past performance is not indicative of future results. Any charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see https://a16z.com/disclosures for additional important information.

4 Apr 201950min