a16z Podcast: The Genetics Of Drug Delivery

It may seem like good apps or services sell themselves. That's what the whole viral thing is all about, right? Wrong, says Daniel Shapero, who helped build LinkedIn's enterprise sales team from a small core group to more than 1,200 people all over the globe. Shapero joins a16z General Partner Peter Levine (an engineer who jumped into sales before taking on his first CEO gig, and who now also teaches a class on the topic at Stanford) to discuss the right way to build a sales organization -- from answering the basic question of why sales?, to hiring, compensation ... and the inevitable culture clash that occurs when salespeople and engineers meet.

4 Mars 201528min

Online marketplaces are growing much faster than e-commerce overall. Why is that? And what new kinds of marketplaces powered by the internet and mobile are we now seeing? a16z's Jeff Jordan and Anu Hariharan share their observations here and also explain what makes marketplace powered by software and reputation work -- as well as how to manage tensions, trust, and marketplace community reactions around change.

18 Feb 201526min

You've heard the story: Slack began as a game. But almost exactly 1 year ago today, the internal tool the team built for its own use became a team communication app that anyone (and especially enterprises) can use -- and is now one of the fastest growing ones at that. It seems like collaboration is "something software should be helping us with” Slack co-founder Stewart Butterfield observes, yet it typically isn't. So what can an app like Slack tell us about how we work today, and how the nature of work will change (fewer meetings? less emails)? Butterfield is joined in this edition of the a16z podcast by a16z board partner Steven Sinofsky and a16z's Benedict Evans. The trio examines the origins of messaging and task management tools (many of which Sinofsky worked on at Microsoft) -- and how the advent of cloud-based services and mobile in particular have changed the requirements for modern workplace tools and information management. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

11 Feb 201538min

Consumers seem content with the mobile duopoly we currently have. So what can be gained from a third mobile operating system? If it's an open computing platform, argues Cyanogen CEO and co-founder Kirt McMaster (in discussion with a16z's Zal Bilimoria), one big win for developers and device makers is access to the guts of an operating system -- and the opportunity to exist as core services rather than simple apps riding on top of an OS. For consumers this means potentially new and unique software for smartphones, tablets, and wearables that take advantage of that tight integration. How else could the next Siri or Gmail take hold on mobile ... without necessarily coming from the likes of Apple and Google?? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

7 Feb 201522min

A crisis can be an opportunity to change your culture. But you have to get through the crisis first, and that starts with getting to the truth of what happened. a16z's Margit Wennmachers, who co-founded The Outcast Agency, and Judy Smith, the founder of a crisis management firm but also "the real life Olivia Pope" (the inspiration behind the ABC show Scandal) draw on their long experience managing all types of crises to walk us through what steps to take when things go bad.

3 Feb 201527min

Apple absolutely crushed its most recent quarter, and unquestionably owns the high-end of the smartphone market, says a16z’s Benedict Evans. So where does Android fit in the ecosystem going forward? Where is the leverage for Google? Not to mention for Facebook, Amazon, and handset-makers like Samsung? Get used to this market complexion for the foreseeable future, Evans argues, with Apple owning the high-end; forked Android-powered devices flourishing at the low-end; and a battle to sell Google-approved Android gadgets in the middle. Until, of course, everything changes yet again.

30 Jan 201528min

Virtual reality (VR) -- and augmented reality (AR) -- seem to be everywhere these days, showing up in demos and offerings from the world's biggest gadget makers to the Hollywood, gaming, and media crowds. But what's the difference between VR and AR? Is one better suited for work vs. play? What happens when you are building experiences -- and an entirely new visual grammar -- from scratch ... will we actually need standards next? a16z's Chris Dixon and Wired Entertainment's Peter Rubin discuss all this and more on this episode of the a16z Podcast. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

27 Jan 201530min

Tracy Chou from Pinterest, and Chris Granger and Jamie Brandon from Eve, discuss whether coding is a literacy (or as Granger puts it, a "superpower" ). But as software infuses every industry and much of our lives, do we all really need to start writing code? Or is a less hands-on approach -- educating ourselves about what software can (and can't) do, and the basic architecture behind its creation -- the most useful way to gain software literacy for most people? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

19 Jan 201524min