a16z Podcast: The Scientific Revolution of Ancient DNA

Nir Eyal and Product Hunt's Ryan Hoover, the authors of "Hooked, How to Build Habit-Forming Products," discuss the theory and practice of the book as the publish date of a new edition approaches. Nir lays out the four steps integral to any habit-forming product -- trigger, action, reward, investment -- and Ryan describes how those same steps apply to the fast-growing Product Hunt. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

15 Sep 201420min

Have we as a culture become expert at globalizing industries, but are we failing when it comes to truly world-changing technological breakthroughs? Is competition bad for business? Should you bother with creating the “nth” social network (the answer is no)? Chris Dixon and Blake Masters dig into these themes, plus “power laws” and the importance of secrets from Peter Thiel's new book with Masters, “Zero to One.” Dixon tries to pry a secret from Masters, but they aren’t called “secrets” for nothing.

12 Sep 201418min

NFC (near field communication) technology has been around for about a decade, and with the exception of transit cards mostly outside the United States it’s gone nowhere. Now Apple has debuted Apple Pay. Has Apple filled in the gaps in terms of user experience, sheer number of devices, and retail footprint to finally make NFC work? In six months will we all be swiping our phones at every coffee joint and grocery store? Once Apple has virtualized your credit cards, what comes next? Benedict Evans is joined by a16z’s Frank Chen and Zal Bilimoria to discuss the latest from Cupertino’s finest around payments, the long-awaited Apple Watch, and a bigger (and biggest) iPhone.

10 Sep 201433min

It’s a problem most entrepreneurs would love to face, a massive valuation offer from investors for the startup they’ve been killing themselves over. But what terms come along with that big number? In this segment a16z’s Scott Kupor is joined by two startup CEOs to pick apart the topic of valuations – serial entrepreneur Danny Shader, founder of PayNearMe, and Danielle Morrill, co-founder of Mattermark.

8 Sep 201425min

Profitless Ponzi scheme, or the greatest company in the world led by an absolute genius? Amazon is a polarizing company. Quarter after quarter, as it grows ever larger gobbling up categories and adding businesses, Amazon manages to produce exactly no profit. It’s as if its founder and CEO Jeff Bezos engineered it that way. He has, and Bezos will continue on the same profitless path, says Benedict Evans in conversation with Ben Horowitz in this segment of the a16z podcast. Benedict and Ben (yeah, we know, two Bens) examine the company Bezos has constructed, and why, for Bezos at least as opposed to nervous investors, it works so well. How one of the world's great founders gets away with building a massive public company his way. Be sure to check out Benedict's post on the topic for all the charts and numbers: http://a16z.com

5 Sep 201417min

Given that physical retail is expensive, what’s the right distribution mix for startups? In this podcast with Tristan Walker (who is building health and beauty brand Walker & Company from scratch), we hear Ron Johnson's lessons learned from arguably the world’s most successful physical retail outlet: the Apple Store -- as well as a discussion of the challenges of brand and retail in a multichannel world. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

3 Sep 201427min

Teenage siblings Ima, Asha and Caleb Christian from Atlanta, Georgia join Ben Horowitz for a discussion about the motivation and origins of their new app, Five-O. In the aftermath of the tragedy in Ferguson, Missouri, the young developers built Five-O as a tool to rate and document interactions -- good and bad -- with the police. Ben and the Five-O team discuss the origins and technical underpinnings of the app. Rapper Nas makes an appearance, offering his own experience with the police, and why efforts like Five-O work towards a solution that both citizens and police should get behind. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

28 Aug 201413min

The five-year anniversary segment with a16z founders Ben Horowitz and Marc Andreessen picks up with a discussion of Clayton Christensen's theories around disruption. Why Christensen's thinking is very much on the mark today, and how his theories help guide the firm in making decisions about what NOT to invest in. Ben offers one of the things he wished he had known as a young CEO, and Marc describes a trait that every great entrepreneur possesses. Part two of two.

26 Aug 201416min