Uncontrolled Spread: Science, Policy, Institutions, Infrastructure
a16z Podcast20 Sep 2021

Uncontrolled Spread: Science, Policy, Institutions, Infrastructure

There's no question technology played a huge role in the recent/current pandemic, including especially in the plug-and-play engineering and incredibly fast development behind the mRNA vaccines... But is there an even bigger role for the private sector, not just government, to play (and partner) when it comes to key infrastructure for future such emergencies, and even beyond?

Especially given how faulty the translation of institutional science to policy and public health measures turned out to be -- for instance, with "6 feet" of social distancing, or with fomite (vs. aerosol) transmission of COVID. And why are we still talking about the same, not specific, vaccine booster for the Delta variant? What can we learn about real-world evidence, other clinical trial approaches, and progressive (vs. binary) EUA approvals when it comes to public health emergencies? Are capabilities like genomic surveillance and mapping strains -- which require layers of technology, real time -- sitting in the right places?

In this special book-launch episode of the a16z Podcast, former FDA commissioner Dr. Scott Gottlieb -- author of the upcoming new book, Uncontrolled Spread: Why COVID-19 Crushed Us, and How We Can Defeat the Next Pandemic -- shares insights on the above, and revealing stories from behind the scenes. Do we need a new entity to manage public health through a national security lens, and is the government capable? Gottlieb debates this and other probing questions from a16z co-founder Marc Andreessen (who famously wrote "It's time to build"); a16z bio general partner Vineeta Agarwala MD, Phd (who has spoken about the trials of clinical trials, practiced medicine during the pandemic, and more); and founding a16z bio general partner Vijay Pande PhD (who, among other things, founded the distributed computing project Folding@Home which pivoted to COVID proteins).

One thing's for sure -- with this COVID crisis, we're at an inflection point between old and new technology -- whether it's in how we make vaccines, or how we apply the fields of synthetic biology and genetic epidemiology in public health response. So now's the time to look both backward, and forward, to really change things...

Avsnitt(900)

a16z Podcast: The (Definite) Optimism of Peter Thiel

a16z Podcast: The (Definite) Optimism of Peter Thiel

What is Silicon Valley’s greatest reigning monopoly? How did PayPal manage to emerge from the dotcom implosion? Can you build a great tech company and keep it private forever? And how did Elon Musk manage to wreck an uninsured, million-dollar car with Peter Thiel in the passenger seat speeding on the way to a VC meeting? Marc Andreessen and Thiel discuss all of it in a wide-ranging conversation that toggles off the topics in Thiel’s new book “Zero to One.”

17 Okt 201446min

a16z Podcast: Startups as Science Experiments -- Can VC Disrupt Academia?

a16z Podcast: Startups as Science Experiments -- Can VC Disrupt Academia?

It's a myth that startups happen in isolation. Those legendary two people in a garage are often building on the deep and basic research -- long funded by government and conducted in universities -- that has come before it. But with the advent of the internet, what's the future of peer-to-peer collaborations and startups-as-"science experiments"? Can venture capital disrupt academia… and vice versa? And finally, what's the secret to universities like Stanford making money off the entrepreneurial ideas coming out of them? (Hint: It starts with a 'p'. But not what you think.) a16z's new professor in residence Vijay Pande interviews Marc Andreessen at our recent Academic summit on these topics, as well as 'regulatory arbitrage', how to mix humanities and science, and what Marc would have majored in if he were 18 today.

2 Okt 201423min

a16z Podcast: For Buzzfeed Sharing is the Metric that Matters

a16z Podcast: For Buzzfeed Sharing is the Metric that Matters

Jonah Peretti is building BuzzFeed to “inform, inspire and entertain” in a world where news and entertainment is increasingly passed around on social networks and consumed on smartphones. Chris Dixon, who is on the board of BuzzFeed as part of Andreessen Horowitz’s recent investment in the startup, sat down with Peretti to talk about building a media company from scratch. If editorial success is driven by digital word-of-mouth, and mountains of data about what people like to read and watch, what does Peretti do differently? Why do BuzzFeed’s lists work so well? Does video finally make financial sense? And why, even if it’s a traffic monster now, is Peretti not religious about any particular format -- including lists. (For more on Dixon’s take on the media business, and BuzzFeed’s “full stack” approach check out this recent post: http://cdixon.org/2014/08/10/buzzfeed/) The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

18 Sep 201426min

a16z Podcast: Reinventing Media

a16z Podcast: Reinventing Media

Software, and the billions of transistors that power it, has brought about massive change to all kinds of industries, but none more so than the news business. Today, distribution doesn’t come from the back of trucks, but from Facebook, Twitter and all across the social web. Relationships with readers and viewers have become a two-way conversation. It’s not news that the traditional business model of news has come under extreme pressure, but there is growing evidence that the reach of media outlets -- and in many ways the opportunity -- has never been greater. In today’s unending news cycle, the latest story, video or graphic is only a tap away from a potential audience of billions around the world. Andreessen Horowitz’s Margit Wennmachers leads a conversation about the road ahead for good journalism and the business of news with Claire Cain Miller from the New York Times, Alexis Madrigal from The Atlantic, and CNET’s Connie Guglielmo.

17 Sep 201435min

a16z Podcast: Trigger, Action, Reward, Investment -- Four Steps for Habit-Forming Products

a16z Podcast: Trigger, Action, Reward, Investment -- Four Steps for Habit-Forming Products

Nir Eyal and Product Hunt's Ryan Hoover, the authors of "Hooked, How to Build Habit-Forming Products," discuss the theory and practice of the book as the publish date of a new edition approaches. Nir lays out the four steps integral to any habit-forming product -- trigger, action, reward, investment -- and Ryan describes how those same steps apply to the fast-growing Product Hunt. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

15 Sep 201420min

a16z Podcast: Secrets, Power Laws, and Technology – The Ideas of  “Zero to One”

a16z Podcast: Secrets, Power Laws, and Technology – The Ideas of “Zero to One”

Have we as a culture become expert at globalizing industries, but are we failing when it comes to truly world-changing technological breakthroughs? Is competition bad for business? Should you bother with creating the “nth” social network (the answer is no)? Chris Dixon and Blake Masters dig into these themes, plus “power laws” and the importance of secrets from Peter Thiel's new book with Masters, “Zero to One.” Dixon tries to pry a secret from Masters, but they aren’t called “secrets” for nothing.

12 Sep 201418min

a16z Podcast: Apple Takes on Payments and Your Wrist

a16z Podcast: Apple Takes on Payments and Your Wrist

NFC (near field communication) technology has been around for about a decade, and with the exception of transit cards mostly outside the United States it’s gone nowhere. Now Apple has debuted Apple Pay. Has Apple filled in the gaps in terms of user experience, sheer number of devices, and retail footprint to finally make NFC work? In six months will we all be swiping our phones at every coffee joint and grocery store? Once Apple has virtualized your credit cards, what comes next? Benedict Evans is joined by a16z’s Frank Chen and Zal Bilimoria to discuss the latest from Cupertino’s finest around payments, the long-awaited Apple Watch, and a bigger (and biggest) iPhone.

10 Sep 201433min

a16z Podcast: Raising Money and Valuing Startups -- What Happens When Things Don't Go As Planned?

a16z Podcast: Raising Money and Valuing Startups -- What Happens When Things Don't Go As Planned?

It’s a problem most entrepreneurs would love to face, a massive valuation offer from investors for the startup they’ve been killing themselves over. But what terms come along with that big number? In this segment a16z’s Scott Kupor is joined by two startup CEOs to pick apart the topic of valuations – serial entrepreneur Danny Shader, founder of PayNearMe, and Danielle Morrill, co-founder of Mattermark.

8 Sep 201425min

Populärt inom Business & ekonomi

framgangspodden
badfluence
varvet
uppgang-och-fall
rss-borsens-finest
svd-ledarredaktionen
avanzapodden
fill-or-kill
affarsvarlden
borsmorgon
dynastin
rss-dagen-med-di
rikatillsammans-om-privatekonomi-rikedom-i-livet
rss-kort-lang-analyspodden-fran-di
kapitalet-en-podd-om-ekonomi
lastbilspodden
ett-rikare-liv
market-makers
ekonomiekot-extra
tabberaset