#560: Building a Research OS: From Django to 30,000 Samples
In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three cities and a dozen hospitals. He asked around about ...
26 Aug 1h 2min
#559: 12 Things You Should (and Shouldn't) Do in AWS
Your site is down. It's 3am. Is it a bug, a bill, or a breach? You can't tell yet, and everyone is watching you find out. Matt Lea has spent fifteen years being the person companies call when an outag...
19 Aug 1h 7min
#558: Hyper-Personal Software with Python
Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There are two unwritten rules around it: don't change it,...
10 Aug 1h 2min
#557: Security of everything at PyCon 2026
Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, secur...
2 Aug 1h 8min
#556: Updates on Django's Async Story
For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half-finished. Well, that story just got rewritten, literally, an...
26 Juli 1h 4min
#555: Marimo Pair - A Canvas for Agent + Developers Collaboration
Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But that is not how data work feels. You load something...
13 Juli 1h 4min
#554: Trustworthy AI in Healthcare and Longevity
You ask an AI a question and it answers with total confidence. Most of the time, a confidently wrong answer is just an annoyance. But what if the question is medical, and there's a real patient on the...
10 Juli 1h
#553: All of our tools
This episode is a fun crossover from our Python news and tips podcast, Python Bytes. We have had some big changes over there. Brian Okken has moved on and Calvin Hendryx-Parker has joined the show as ...
26 Juni 55min
