The Itch: Allergies, Asthma, Eczema & Immunology13 Feb 2025

#101 - What is Type 2 Inflammation?

What do asthma, eczema, EoE, and nasal polyps have in common? They all stem from Type 2 inflammation!

Type 2 inflammation is a major cause of many allergic and inflammatory conditions, yet it remains widely misunderstood. In this first episode of our four-part series on Type 2 Inflammation, we discuss the basics, unpack its impact on the immune system, explain how it contributes to chronic inflammation in the body, and explain why it matters for treatment and management.

What we cover in our episode about Type 2 Inflammation

Understanding Inflammation: Inflammation is your body’s natural defence mechanism, but it can become problematic when it turns chronic.
Normal vs. Chronic Inflammation: Not all inflammation is bad! Learn the difference between the body’s normal immune response and long-term chronic inflammation.
What Sets Type 2 Inflammation Apart? Unlike other immune responses, Type 2 inflammation involves a specific pathway.
Key Players in Type 2 Inflammation: Th2 cells, cytokines (IL-4, IL-5, IL-13), IgE antibodies, and eosinophils.
Measuring Type 2 Inflammation: How blood tests can help determine if Type 2 inflammation is contributing to your symptoms.

Want to know more? Type 2 Inflammation Overview – Explains the role of Type 2 inflammation in conditions like asthma and nasal polyps.

This podcast is for informational purposes only and does not substitute for professional medical advice. If you have any medical concerns, always consult with your healthcare provider.

Produced in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

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