Marc Andreessen & Jack Altman: Venture Capital, AI, & Media
a16z Podcast11 Juni

Marc Andreessen & Jack Altman: Venture Capital, AI, & Media

In this episode Jack Altman, CEO of Lattice and host of Uncapped, interviews Marc Andreessen on how venture capital is evolving — from small seed funds to billion-dollar barbell strategies — and why today’s most important tech companies don’t just build tools, they replace entire industries. They cover:

  • The end of “picks and shovels” investing
  • Why missing a great company matters more than backing a bad one
  • The power law math behind fund size and asymmetric returns
  • AI as the next computing platform — and a test for Western civilization
  • Preference falsification, media power, and what founders can’t say out loud

This is a conversation about ambition at scale, the structure of modern venture, and the deep forces reshaping startups, innovation, and power.

Resources:

Listen to more from Uncapped: https://linktr.ee/uncappedpod

Find Jack on Xhttps://x.com/jaltma

Find Marc on X: https://x.com/pmarca

Find Uncapped on X: https://x.com/uncapped_pod

Timecodes:
00:00 What You Can’t Say

01:20 Founders, Funders, and the Future

02:00 Fund Size and Power Law Math

06:45 From Tools to Full Stack Startups

10:00 Market Sizing and Asymmetric Bets

13:00 Public Markets Mirror Venture Dynamics

17:00 The Barbell Strategy in Venture

20:00 The Conflict Dilemma in Venture

25:00 Staying in Early-Stage Venture

29:30 The Death of the Middle

32:00 Why It’s So Rare to Build a New Top VC Firm

35:00 The Case for Power in Venture

37:45 Limiting Factors for Big Companies

41:00 AI as the Next Computing Platform

45:30 Betting on Startups, Not Incumbents

48:00 How a16z Thinks About Risk

51:00 Building a Top-Tier GP Team

55:00 Taste, Timing, and Getting Into the Scene

57:00 Raising Capital Is the Easy Part

1:00:30 AI’s Existential Stakes

1:05:00 Autonomous Weapons, Ethics, and War

1:11:00 Tech, Government, and Power

1:13:00 Media, Mistrust, and Narrative Collapse

1:24:00 Preference Falsification and Cultural Cascades

1:32:00 The Thought Experiment

1:33:00 Career Advice for Young Builders

1:35:00 Marc vs. the Huberman Protocol

1:39:30 What Would Prove You Right?

Stay Updated:

Let us know what you think: https://ratethispodcast.com/a16z

Find a16z on Twitter: https://twitter.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://x.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

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a16z Podcast: Latinos and the Tech Economy -- U.S. Reps. Sanchez and Gallego Talk Bridging the Gaps

a16z Podcast: Latinos and the Tech Economy -- U.S. Reps. Sanchez and Gallego Talk Bridging the Gaps

There is a gap between the technology industry and the fastest growing portion of today’s workforce and the workforce of the future: Latinos -- argue U.S. Representatives Loretta Sanchez (California) and Ruben Gallego (Arizona), both members of Congress. How can we bring more Latinos -- and other underrepresented populations -- into the tech industry, and what roles do both government and fast-moving tech companies have to play? Especially if tech entrepreneurs and government have a hard time working together? “We have the innovators...[but] how do you move that Latino innovator into the mainstream?” asks Sanchez in this episode of the a16z Podcast.

9 Juli 201524min

a16z Podcast: Is Entrepreneurship a Universal Language?

a16z Podcast: Is Entrepreneurship a Universal Language?

In this special international edition of the a16z Podcast, Mohsen Malayeri, co-founder of Avatech -- one of the more prominent startup accelerators in Iran among many (much like Y Combinator in the U.S.) -- talks to guest interviewer Christopher Schroeder (former entrepreneur, D.C. investor, and author of Startup Rising) about startups in Iran. What happens when you have a "mobile-first" startup ecosystem? Is this about trying to be yet another Silicon Valley (and if so, are we just substituting a form of technocracy for theocracy)? Silicon Valley isn't a religion, observes Malayeri, but entrepreneurship IS "a common language which has no border". This is the third installment in a special series on tech startups in Iran, part of a larger theme around global tech and how software -- including mobile -- is eating the world … and creating new opportunities within it.

1 Juli 201542min

a16z Podcast: Layering Tech and Culture in Iran

a16z Podcast: Layering Tech and Culture in Iran

In this special international edition of the a16z Podcast, Nazanin Daneshvar, co-founder and CEO of Takhfifan, the "Groupon of Iran", shares her experiences and broader observations about the startup ecosystem and tech infrastructure in Iran with guest interviewer Christopher Schroeder (former entrepreneur, D.C. investor, and author of Startup Rising). How did she do it? (Hint: With a bit of subterfuge and clever cloaking.)What are the attitudes toward failure in a time and place where startups aren't really considered a real thing? This is the second installment in a special series on tech startups in Iran, part of a larger theme around global tech and how software -- including mobile -- is eating the world … and creating new opportunities within it.

30 Juni 201519min

a16z Podcast: A Conversation With the Inventor of Spark

a16z Podcast: A Conversation With the Inventor of Spark

One of the most active and fastest growing open source big data cluster computing projects is Apache Spark, which was originally developed at U.C. Berkeley's AMPLab and is now used by internet giants and other companies around the world. Including, as announced most recently, IBM. In this Q&A with Spark inventor Matei Zaharia -- also the CTO and co-founder of Databricks (and a professor at MIT) -- on the heels of the recent Spark Summit, we cover the difference between Hadoop MapReduce and Spark; what are the ingredients of a successful open source project; and the story of how Spark almost helped a friend win a million dollars.

24 Juni 201519min

a16z Podcast: Investing in Communities

a16z Podcast: Investing in Communities

Investing to make a return both financial AND societal isn't new, but the opportunities to reach and build businesses in communities that have been underserved by tech are larger than ever. One example is the business opportunity presented by hairstylist platform Mayvenn, which a16z recently backed. In this segment of the a16z Podcast, Kesha Cash (founder and general partner of the Impact America Fund, also an investor in Mayvenn) discusses how she puts her fund’s money to work in markets that target underserved Americans. Cash is joined by a16z’s Tawny Holguin (who leads our seed and early scouting efforts) to breakdown the intricacies -- and opportunities -- of so-called “impact investing.” Do core business principles change at all? But then how does impact get measured? And what happens when you connect more communities to tech?

22 Juni 201524min

a16z Podcast: The Rise of the Quasi-IPO

a16z Podcast: The Rise of the Quasi-IPO

"This time is different." But it's always different! So what's going on now in the public markets? Why does this even matter? For one thing, tech markets have grown significantly. And one big reason is internet and mobile. It's like a multiplier for the market size and opportunity. In this episode of the a16z Podcast, Andreessen Horowitz managing partner Scott Kupor, mobile analyst Benedict Evans, and corp dev research partner Morgan Bender break down a slide deck we recently shared, including answers to what all these so-called “unicorns” are, how it affects venture capital and the funding landscape, and how we define a "quasi-IPO." The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

17 Juni 201529min

a16z Podcast: Location, Location, Location -- and Mobile

a16z Podcast: Location, Location, Location -- and Mobile

Pick your metaphor: Smartphones are "remote controls" for the physical world, or perhaps, as Steve Cheney argues, they're "cursors for the physical world". Either way, it's clear that the age of mobile is here, GPS is not enough, and with sensors all around us -- both outdoors and in indoor locations -- it's finally time for truly context-aware computing. But what will that take, both content- and design-wise -- is it all just about eliminating friction? And how are players like Apple and Google positioning themselves for this micro-mapped world? a16z's Benedict Evans and Estimote's Steve Cheney talk about these questions and more in this episode of the a16z Podcast...

11 Juni 201522min

a16z Podcast: Dealing with Corporate Dealmakers -- When to Talk to Corp Dev

a16z Podcast: Dealing with Corporate Dealmakers -- When to Talk to Corp Dev

Every meeting a busy founder takes is time away from building the company. So it’s understandable why engaging corporate development groups is believed to be a waste of time, unless you’re selling your company. But... there ARE good reasons to engage corporate development. You just have to know when, and how. And what to avoid! On this episode of the a16z Podcast, operating partner Jamie McGurk, and Tyson Clark and James Loftus (veterans of corporate development from companies like Google, Oracle, and Yahoo) share advice for founders talking to corporate development.

10 Juni 201522min

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