02_05 Management of Metastatic Hormone Positive Breast Cancer
1. Endocrine Resistance: Definition and Mechanism 2. Role of AI with and without CDK4/6 inhibitors 3. Later line management of metastatic disease 4. Informative Censoring and t...
6 Dec 202232min
02_04 Recurrence risk scores and CDK inhibitors for Early Breast Cancer
1. Recurrence Risk Scores 2. TailorRx, RxPonder, MINDACT Trials Overview 3. Introduction to CDK 4/6 inhibitors 4. PALLAS and MONARCH-E Discussion Citations As always, citations...
19 Nov 202231min
02_03 Adjuvant endocrine therapy for early breast cancer
1. Tamoxifen, its development, mechanism and benefits 2. Aromatase inhibitors and their benefit in post-menopausal state 3. Nuances on extended endocrine therapy beyond 5 years 4. ...
29 Okt 202231min
02_02 Chemotherapy Options and Bisphosphonates in Early Breast Cancer
1. First, second, and third generation chemotherapy regimens 2. Considerations for anthracyclines 3. Considerations for taxanes 4. Adjuvant bisphosphonates Citations As always...
11 Okt 202225min
02_01 An Overview of Considerations for Early Breast Cancer
1. History of surgery and radiation for breast cancer 2. Indication and goal of adjuvant systemic therapy (incl cell-kill hypothesis) 3. Overview of breast cancer subtypes 4. S...
27 Sep 202226min
01_13 Anal Squamous Cell Carcinoma
1. Overview of disease site 2. Management of localized disease 3. Surveillance 4. Metastatic Disease Citations As always, citations, and sources include education from our resp...
14 Sep 202216min
01_12 Rectal Cancer – TNT (Total Neoadjuvant Therapy) and Immunotherapy
1. RAPIDO Trial 2. PRODIGE-23 Trial 3. OPRA Trial 4. Evidence for non-operative potential in MSI-H tumors with immune checkpoint inhibition Citations As always, citations, a...
1 Sep 202225min
01_11 Rectal Cancer – An Overview of the Challenges and Basics of Management
1. Anatomy, definitions, and unique considerations vs colon cancer 2. Surgical modalities and patterns of failure 3. Perioperative radiation and chemoradiation 4. Evidence to s...
18 Aug 202226min
