
102: Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort
Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort Music:Enjoy the music based on this article at the end of the episode. Support:Base by Base is independent and ad-free — no...
10 Elo 202514min

101: JAK2 Inhibition Selects RAS-Mutant Clones in Myelofibrosis
JAK2 Inhibition Selects RAS-Mutant Clones in Myelofibrosis Music:Enjoy the music based on this article at the end of the episode. Support:Base by Base is independent and ad-free — no sponsors, no pa...
9 Elo 202518min

100: ALMA: Epigenomic diagnosis & prognosis of AML
Marchi F et al., Nature Communications - This study builds the Acute Leukemia Methylome Atlas (ALMA) from 3,314 patient methylomes and presents three models—ALMA Subtype, AML Epigenomic Risk, and a 38...
8 Elo 202514min

99: NXT2: a testis-specific RNA export hub essential for human spermatogenesis
Dicke A-K et al., Nature Communications - Proteomics, molecular and genetic analyses identify NXT2 as the predominant NXT protein in the human testis that binds NXF1, NXF2 and NXF3 and associates with...
7 Elo 202514min

98: Cell Marker Accordion: Interpretable Single-Cell & Spatial Annotation
Busarello E et al., Nature Communications - This episode covers the Cell Marker Accordion, an integrated marker database plus R package and Shiny app that weights marker genes by specificity and evide...
6 Elo 202519min

️ 97: Pancreatic Cancer Genomics: Insights from the COMPASS Trial
️ Episode 97: Pancreatic Cancer Genomics: Insights from the COMPASS Trial In this episode of PaperCast Base by Base, we explore how integrated whole genome and transcriptome sequencing uncovers clinic...
5 Elo 202521min

️ 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease
️ Episode 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease In this episode of PaperCast Base by Base, we explore a large-scale proteomic study comparing cerebro...
4 Elo 202516min

95: Mitochondria transfer: biotech strategies and clinical hurdles
Kubat GB et al., Nature Communications - This Perspective surveys recent biotechnological advances that enhance mitochondria transfer and transplantation (MTT) — including surface functionalization, e...
3 Elo 202519min















