NSH Poster Podcast (2025): CelLockTM and Axlab: A mutual symbiotic relationship resulting in increased patient care quality.

Poster Title: CelLockTM and Axlab: A mutual symbiotic relationship resulting in increased patient care quality.

Authors: Clifford M Chapman ( Medi-Sci Consultants), Karla Escobar (Axlab -US), Timm Piper (Axlab –US)

Abstract: An ever increasing number of tiny specimens are received in histology laboratories every day. Fine needle aspirates, needle biopsies, gastrointestinal and skin biopsies, along with research specimens such as organelles: all pose challenges in receiving, processing and preparing stained slides from such specimens. Axlab is a Danish based company founded in 1993 which specializes in finding novel solutions for pathology laboratories. Axlab recently announced the release of their AS-410M automated sectioning equipment. Receiving FDA clearance in 2024, this equipment has been successfully implemented worldwide, resulting in enhanced section quality and increased workflow efficiency. CelLockTM is an innovative standardized method for collecting individual cells and small tissue fragments for subsequent routine, immunohistochemical and molecular pathology diagnostic and investigative techniques. The CelLock method, which utilizes a novel product CelLGelTM , results in the collection and retention of 99.9% of the original specimen within a paraffin embedded cell-block. In addition, the specimen is precisely located within the paraffin block, close to the surface, and is identified by a marker to cue when sections should be taken. Axlab is currently investigating the use of CelLock and CelLGel in the preparation of cell blocks which can be precisely sectioned on their automated sectioning equipment. The initial results are presented in this poster.