Vitamin C Serums Explained: How They Work, How to Use Them & Which Ones Actually Work

Antioxidants are everywhere in skincare but few ingredients are as well-studied, misunderstood, or overcomplicated as vitamin C. In this episode of the After Hours Skin Clinic, consultant dermatologists Dr Emma Craythorne and Dr Ellie Rashid revisit one of our most requested topics: topical vitamin C. They break down the science behind how vitamin C works on the skin, what benefits are genuinely evidence-based, and how to use it properly for maximum results. From collagen production and pigmentation to oxidative stress and UV protection, this episode explains why vitamin C remains the gold-standard antioxidant in dermatology and why drinking it is not the same as applying it to your skin. This episode also covers: What antioxidants actually do at a cellular level Why vitamin C is different from other antioxidants The only form of vitamin C supported by strong clinical evidence Ideal strength, formulation, and pH for effectiveness Why vitamin C should only be used in the morning Common formulation mistakes that make vitamin C ineffective How packaging, expiry dates, and stability affect results Which skin types benefit most and who should be cautious If you’ve ever wondered whether vitamin C is worth the investment, how to choose the right one, or why some formulas work and others don’t, this episode gives you clear, practical, science-backed answers. Products mentioned: Skinceuticals C E Ferulic Skinceuticals Silymarin CF Serum For Blemish Prone Skin Skinceuticals Phloretin CF Gel For Skin Discolouration As always, this podcast is for educational purposes and does not replace personalised medical advice. Klira - Founded by Dr Emma Craythorne, Klira is a bespoke luxury skincare formula prescribed by dermatologists. You may hear it mentioned from time to time on the podcast and if you want to find out more head over to klira.skin _____ Have any questions? Send them over to ahsc@raconteur.tv Find us on Instagram @AfterHoursSkinClinic _____ Producer: Ella Blaxill Series Editor: Eve Streeter Music by Simon Elms. This is a Raconteur Studios Production. Learn more about your ad choices. Visit podcastchoices.com/adchoices