The Lead Episode 138: A Discussion of Safety, Efficacy, and Mid-Term Outcomes of Pulsed Field Ablation for Cavotricuspid Isthmus–Dependent Flutter: Real-World Data From a Major Health System Registry

Join Digital Education Committee member and podcast host Deep Chandh Raja, MBBS, MD, PhD, along with this week's guest contributors, Senthil Thambidorai, MD, FHRS and Lee Karl Thien, MD, CCDS for this week's episode.

This real-world registry study evaluated the safety, feasibility, and mid-term outcomes of pulsed field ablation (PFA) for cavotricuspid isthmus (CTI)–dependent atrial flutter. Acute bidirectional CTI block was achieved in nearly all patients, with a low complication rate and high freedom from recurrent flutter at mid-term follow-up. The findings suggest that PFA is an effective non-thermal alternative for typical atrial flutter ablation, though long-term durability and comparisons with conventional thermal energy sources require further investigation.

Learning Objectives

• Describe the procedural success rates and safety profile of pulsed field ablation for CTI-dependent atrial flutter.
• Compare pulsed field ablation with traditional thermal ablation strategies for typical atrial flutter.
• Discuss the role of emerging ablation technologies in the management of supraventricular tachyarrhythmias.

Article Authors
Juan F. Rodriguez-Riascos, MD, Hema S. Vemulapalli, MBBS, Poojan Prajapati, MBBS, Padmapriya Muthu, MBBS, James Y. Kim, MD, Dan Sorajja, MD, Win-Kuang Shen, MD, Hicham El Masry, MD, Mayank Sardana, MBBS, MD, Arturo M. Valverde, MD, Thomas M. Munger, MD, and Komandoor Srivathsan, MD

Podcast Contributors
Senthil Thambidorai, MD, FHRS
Lee Karl Thien, MD, CCDS
Deep Chandh Raja, MBBS, MD, PhD

All relevant financial relationships have been mitigated.

Host and Contributor Disclosure(s):

D. Raja
Nothing to disclose.

S. Thambidorai Nothing to disclose.

L. K. Thien Nothing to disclose.

Staff Disclosure(s) (note: HRS staff are NOT in control of educational content. Disclosures are provided solely for full transparency to the learner):

S. Sailor: No relevant financial relationships with ineligible companies to disclose.