#434 - [Journal Club] - 📌 Could Intranasal Breast Milk Be the Next Adjunct Therapy for HIE?

#434 - [Journal Club] - 📌 Could Intranasal Breast Milk Be the Next Adjunct Therapy for HIE?

Send us Fan Mail In this Journal Club episode, Daphna presents the F-NeoBright trial — a pilot feasibility and safety study out of Hungary exploring intranasal fresh breast milk administration in neonates with moderate to severe HIE undergoing therapeutic hypothermia. With so few adjunct therapies available beyond cooling, the idea of harnessing breast milk's rich bioactive components — including neurotrophic growth factors, cytokines, and multipotent stem cells — to support the developing br...

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Episoder(937)

#462 - [Journal Club] - 📌 After HEAL Does a Second Trial Close the Book on EPO?

#462 - [Journal Club] - 📌 After HEAL Does a Second Trial Close the Book on EPO?

Send us Fan Mail We already had HEAL, so why run this trial at all? Daphna brings PAEAN from JAMA Pediatrics, a phase three trial across 24 units in Australia, New Zealand, and Singapore that gave hig...

1 Sep 22min

#462 - [Journal Club] - 📌 After LISA Does CPAP Perform as Well as NIMV Below 30 Weeks?

#462 - [Journal Club] - 📌 After LISA Does CPAP Perform as Well as NIMV Below 30 Weeks?

Send us Fan Mail Most trials comparing CPAP and NIMV leave a lingering doubt about whether surfactant explained the difference. This one does not. Ben brings a multicenter noninferiority trial from JA...

31 Aug 20min

#461 - [đŸ«€ From The Heart] - Blue Baby, Gray Baby: Severe LV Dysfunction Masquerading as PPHN

#461 - [đŸ«€ From The Heart] - Blue Baby, Gray Baby: Severe LV Dysfunction Masquerading as PPHN

Send us Fan Mail A term newborn looks fine on mom's chest, then crashes within minutes. By the time transport arrives, there's a pH of 6.9, a lactate over 10, and a baby already intubated and on surfa...

24 Aug 55min

#460 - Reading as a neuroprotective intervention

#460 - Reading as a neuroprotective intervention

Send us Fan Mail Why does reading in the NICU still feel optional when the evidence says otherwise? Daphna sits down with Paige Pedroli, author of the Nic Zoo book and two-time NICU mom, and Dr. Raque...

21 Aug 46min

#459 - Which AI tools are actually ready for the NICU right now?

#459 - Which AI tools are actually ready for the NICU right now?

Send us Fan Mail Is your EMR actually built for neonatology, or just retrofitted to survive it? Ben sits down with Dr. Lindsey Knake, clinical assistant professor and associate chief health informatio...

17 Aug 45min

#458 - 📑 Journal Club - The Complete Episode from August 15th 2026

#458 - 📑 Journal Club - The Complete Episode from August 15th 2026

Send us Fan Mail The full week of Journal Club in one place. Monday, the PLaNT trial of prophylactic CPAP for late preterm infants born by cesarean, with senior author Dr. Edgardo Szyld. Tuesday, whet...

15 Aug 2h

#458 - [Journal Club] - 📌 Can the respiratory severity score show us where a baby is heading?

#458 - [Journal Club] - 📌 Can the respiratory severity score show us where a baby is heading?

Send us Fan Mail The respiratory severity score is one multiplication most of us already do in our heads, mean airway pressure times FiO2. This week Dr. Dinushan Kaluarachchi joins Journal Club to wal...

14 Aug 26min

#458 - [Journal Club] - 📌 Could a handheld light probe detect NEC before the X-ray does?

#458 - [Journal Club] - 📌 Could a handheld light probe detect NEC before the X-ray does?

Send us Fan Mail NEC still tends to announce itself on an X-ray, usually later than we want. This week Daphna reviews the first-in-human study of broadband optical spectroscopy, a handheld transcutane...

13 Aug 22min

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