Menopause Masterclass: HRT Safety, Patch Absorption, Progesterone Intolerance, and Bone Density

Menopause Masterclass: HRT Safety, Patch Absorption, Progesterone Intolerance, and Bone Density

In this episode of unPAUSED, Dr. Mary Claire Haver answers your most asked questions about hormone therapy, menopause symptoms, and how to advocate for yourself when your doctor doesn't have answers. She walks through who actually qualifies for HRT, what the real contraindications are versus conditions that simply require a different delivery method, and how to think about continuing estrogen, progesterone, and testosterone therapy after 60.

Dr. Haver explains the estrogen patch absorption problem, with research showing that up to 20 percent of women on transdermal therapy never reach physiologic estradiol levels regardless of dose. She breaks down SHBG, the protein that can bind your hormones and render them inactive even when your numbers look adequate on paper, and walks through what optimal estradiol levels look like for bone density and osteoporosis prevention specifically.


Books:

“The Complete Bone and Joint Health Plan: Help Prevent and Treat Osteoporosis and Arthritis,” by Jocelyn Wittstein
“The New Perimenopause,” by Dr. Mary Claire Haver


Resources:

Women’s Health Initiative Estradiol (University of Rochester Medical Center) Meet Dr. Heather Hirsch Alloy Health Midi Health Menopause Quiz Lab Test Checklist Blueprint to close the women's health gap


For full show notes, please click here.

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Episoder(62)

Menopause Masterclass: Why Your Hair Is Thinning and What Works

Menopause Masterclass: Why Your Hair Is Thinning and What Works

In this solo episode of unPAUSED, Dr. Mary Claire Haver tells the truth about hair loss in women over 40 — a medical condition with real, identifiable causes, not a vanity complaint to be dismissed as...

15 Sep 51min

Melinda French Gates Is Fighting to Close the Menopause Funding Gap

Melinda French Gates Is Fighting to Close the Menopause Funding Gap

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Melinda French Gates, philanthropist and founder of Pivotal, to talk about her call for a "menopause revolution" — including the $215 ...

8 Sep 46min

Testosterone Is Not a Male Hormone: Levels, Dosing, and What It Does During Menopause

Testosterone Is Not a Male Hormone: Levels, Dosing, and What It Does During Menopause

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Mohit Khera, board-certified urologist and Professor of Urology at Baylor College of Medicine, where he holds the F. Brantley Scot...

1 Sep 1h 12min

Dr. Mary Claire Haver on Menopause: Recorded Live from LA with Dr. Rena Malik

Dr. Mary Claire Haver on Menopause: Recorded Live from LA with Dr. Rena Malik

This episode of unPAUSED was recorded live at the Wiltern Theater in Los Angeles in front of an audience gathered to talk about perimenopause, menopause, hormones, sex, brain health, and bone health. ...

25 Aug 1h 14min

Listen Again: Build Strength, Live Longer: The Menopause Longevity Blueprint with Dr. Vonda Wright

Listen Again: Build Strength, Live Longer: The Menopause Longevity Blueprint with Dr. Vonda Wright

What if weak bones and muscle loss aren't just "normal aging" but the result of decades of misinformation? In this episode double board-certified orthopedic surgeon Dr. Vonda Wright joins Dr. Mary Cla...

21 Aug 1h 21min

How to Get What You Need From a 15-Minute Doctor's Appointment with Dr. Lucy McBride

How to Get What You Need From a 15-Minute Doctor's Appointment with Dr. Lucy McBride

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Lucy McBride, a Harvard and Johns Hopkins trained primary care physician and author of the new book Beyond the Prescription: A Doc...

18 Aug 1h 7min

Menopause Sleep Reset: A Recovery Plan You Can Start Tonight with Dr. Kristen Holmes

Menopause Sleep Reset: A Recovery Plan You Can Start Tonight with Dr. Kristen Holmes

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Kristen Holmes, Vice President of Performance Science at Whoop and author of the new book Aligned, moving from th...

14 Aug 51min

Menopause and the 3AM Wake Up: What Light, Meal Timing and Hormones Do with Dr. Kristen Holmes

Menopause and the 3AM Wake Up: What Light, Meal Timing and Hormones Do with Dr. Kristen Holmes

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Kristen Holmes, Vice President of Performance Science at Whoop and author of the new book Aligned, to unpack why sleep and circadi...

11 Aug 1h 7min

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