Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213

Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213

The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.

In this solo episode, Dr. Gabrielle Lyon discusses:

  • Why the same drug class can improve sexual function in men with obesity while potentially dampening it in lean or postmenopausal women — and why the deciding factor isn't the drug, it's the body
  • How rapid weight loss raises SHBG, the protein that soaks up free testosterone, so a "normal" total testosterone result can hide a real deficit your bloodwork won't flag
  • Why women make up 60–70% of GLP-1 prescriptions yet the entire evidence base for female sexual function is two case reports, with zero validated questionnaires in any pivotal trial
  • The three-tier action plan for anyone on or about to start a GLP-1 — baseline your sexual function first, get free testosterone tested, and protect muscle with protein and resistance training

Whether you're on a GLP-1 drug or considering one, you'll walk away knowing exactly what to measure before you start and what to watch for after — so a change in your sexual health gets caught as the vital sign it is, instead of being quietly dismissed.

Thank you to our sponsors:


Explore More from Dr. Gabrielle Lyon


Connect with Dr. Gabrielle Lyon:


Chapters

00:00 - Introduction

01:30 - The 35-year-old patient case

04:00 - The question: harm or help?

05:00 - The case against: the 4.5x ED study

06:30 - FAERS database and 182 reports

08:00 - Reward circuits, blood flow, and SHBG

11:00 - Women are 70%, the data is two case reports

12:30 - The case for: detection bias explained

15:00 - Validated studies show testosterone rising

17:00 - GLP-1 vs testosterone therapy and fertility

19:00 - Same receptor, different body

22:00 - Cross-examination: holes in both sides

26:00 - Why the drugs may not all be the same

30:00 - Confidence levels: what Lyon actually believes

33:00 - Tier 1: baseline, hormones, protein, training

35:00 - Tier 2 and 3: dose, molecule switch, adjuncts

36:30 - Your sexuality is a vital sign

If you found this episode valuable, share it with someone who would benefit from it.

Disclaimers: This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(233)

STOP Treating Low Testosterone As Depression: The 160 Reading Navy Doctor Refused | Tim Parlatore

STOP Treating Low Testosterone As Depression: The 160 Reading Navy Doctor Refused | Tim Parlatore

A Navy captain with 24 years of service went to medical for exhaustion, weight gain, and low mood, and was told to see a therapist and eat less. When he asked for a testosterone test his physician ask...

1 Sep 1h 45min

Nobody Told You This About Creatine

Nobody Told You This About Creatine

You might think creatine is a bodybuilder's steroid you have to cycle, load, and fear for your kidneys, but it's a compound your own body already makes from three amino acids, with one of the deepest ...

27 Aug 19min

Are You Aging Faster Than You Should? - Dr. Kristen Holmes

Are You Aging Faster Than You Should? - Dr. Kristen Holmes

Most of what we call "aging" may not be about time at all. It may be a nervous system stuck in stress, quietly draining your sleep, your recovery, and your long-term health.In this episode, Dr. Gabrie...

25 Aug 1h 12min

The Gut Yeast That Brews Ethanol From Every Carb You Eat

The Gut Yeast That Brews Ethanol From Every Carb You Eat

Blowing four times the legal limit on a breathalyzer usually means one thing, but in 2015, a judge dismissed a DWI because the driver's own gut was fermenting alcohol from an ordinary carb-heavy dinne...

20 Aug 20min

The 1 Macronutrient High Performers Skip After 60 | Arthur Brooks, PhD

The 1 Macronutrient High Performers Skip After 60 | Arthur Brooks, PhD

Most people chase happiness as a feeling and wait for certainty before making big decisions, and both instincts quietly backfire. Dr. Arthur Brooks joins Dr. Gabrielle Lyon to break down what happines...

18 Aug 1h 8min

Why You're So Bloated on Ozempic

Why You're So Bloated on Ozempic

You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly ma...

13 Aug 14min

Taryn Smith - The Crash Nobody Warns You About After a Huge Win

Taryn Smith - The Crash Nobody Warns You About After a Huge Win

You'd think fear is what stops you from doing hard things. At 25, with zero rowing experience, Taryn Smith crossed the Atlantic alone. 3,000 miles, 46 days, and I learned that the fear was never the o...

11 Aug 1h 30min

What Glyphosate Does to Your Body

What Glyphosate Does to Your Body

You've probably worried that the glyphosate on your bread is slowly harming you. The evidence points somewhere far less obvious and far more fixable.In this solo episode, Dr. Gabrielle Lyon discusses:...

6 Aug 20min

Populært innen Vitenskap

fastlegen
romkapsel
liberal-halvtime
tingenes-tilstand
jss
tomprat-med-gunnar-tjomlid
rekommandert
forskningno
sinnsyn
villmarksliv
rss-paradigmepodden
tidlose-historier
fjellsportpodden
rss-nysgjerrige-norge
rss-rekommandert
nordnorsk-historie
rss-inn-til-kjernen-med-sunniva-rose
grunnstoffene
nevropodden
rss-fuglehundfolk