TWiM #30: Unraveling melioidosis and insulin resistance

TWiM #30: Unraveling melioidosis and insulin resistance

On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.

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Episoder(364)

363: Why Vegetables Are Good for Your Heart

363: Why Vegetables Are Good for Your Heart

TWiM explains the finding that Bunsen burners do not decrease deposition of microbe-containing particles, and how gut microbiota generate dinitrosyl iron complexes with cardiometabolic benefits. Host...

12 Sep 58min

362: When Gut Bacteria Share Chromosomes

362: When Gut Bacteria Share Chromosomes

TWiM explains how movement of DNA among gut bacteria drive large-scale genome mosaicism, and validation of a method for detection of Cyclospora cayetanensis in outbreak-linked fresh produce. Hosts:  ...

29 Aug 51min

361: Bacteria and Colon Cancer Recurrence

361: Bacteria and Colon Cancer Recurrence

TWiM explains the discovery of an avirulent bacterial signature associated with the development of recurrence following colorectal cancer surgery, and phage-derived proteins and conjugates that induce...

14 Aug 53min

360: Nitrogen Fixation Goes Eukaryotic

360: Nitrogen Fixation Goes Eukaryotic

TWiM explains major implications of the link between plastic pollution and antimicrobial resistance, and the discovery of a new organelle, the nitrogen-fixing nitroplast. Hosts: Vincent Racaniello, Mi...

31 Jul 56min

359: Kin Killing and Metal Hunger

359: Kin Killing and Metal Hunger

TWiM explains how cannibalism shapes biofilm structure and composition in Bacillus subtilis, and the importance of manganese uptake in uropathogenic E. coli during urinary tract infection. Become a ...

18 Jul 48min

358: Gut Microbes and ALS

358: Gut Microbes and ALS

TWiM explains the connection between inflammation caused by microbial glycogen in the gut and amyotrophic lateral sclerosis, and how disruption of cysteine metabolism leads to synthetic lethality and ...

4 Jul 58min

357: Remembering Elio at Tufts

357: Remembering Elio at Tufts

TWiM visits Tufts University School of Medcine and are joined by John Coffin, Michael Malamy, and Verna Manni for a tribute to Elio Schaechter who was chair of Molecular Biology and Microbiology for 2...

15 Jun 55min

TWiM 356: Nanopore to the bone

TWiM 356: Nanopore to the bone

TWiM explains how Streptococcus mitis bacteriocins drive contact-dependent lysis of S. pneumoniae facilitating transformation, and microbial dominance in diabetic foot osteomyelitis determined with na...

28 Mai 49min

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