Food, Drugs, and Tech—100 Years of Public Health
a16z Podcast14 Jan 2020

Food, Drugs, and Tech—100 Years of Public Health


The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a time of enormous upheaval and change, and rapidly emerging technology. The same could be said to be just as true today. From CRISPR to synthetic biology to using artificial intelligence in medicine, our healthcare system is undergoing massive amounts of innovation and change.

Covering everything from gene-editing your dog to tracking the next foodborne outbreak, this wide-ranging conversation between Principal Commissioner of the FDA Amy Abernethy and Vijay Pande, GP on the Bio Fund at a16z, discusses how the agency is evolving to keep pace with the scientific breakthroughs coming, while staying true to its core mission of assessing safety and effectiveness for consumers in the world of food and medicine.

Highlights:

What the FDA looks like today and the key steps of the FDA process to getting a drug/product to market [2:20]

How to manage a culture when mitigating risk is a top priority while aiming to innovate for the future [5:22]

Creative problem-solving in times of crisis, such as the Opioid crisis [9:58]

Preparing for and preventing drug shortages at scale [13:30]

How advances in bioengineering are transforming healthcare [16:00]

How the FDA is thinking about n=1 therapies and its applications in the future [18:54]

The future of healthcare privacy [26:10]

The ways the clinical trial process are shifting [29:26]

Innovations in Bioengineering as they relate to regulating food in the future [36:02]

How the FDA handles foodborne illnesses and its plans to innovate food safety [39:12]

Discussion about the next 100 years of the FDA [41:25]

Episoder(908)

a16z Podcast: Enough with the Old Stuff -- Time for New Questions in Mobile

a16z Podcast: Enough with the Old Stuff -- Time for New Questions in Mobile

It's been a long and (at times) interesting battle pitching iOS vs. Android. It's time to let it go, says a16z's Benedict Evans. It's time to move on to a new set of questions -- and ideas -- in mobile. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

17 Des 201436min

a16z Podcast: Gateway Gadgets to the Internet of Things

a16z Podcast: Gateway Gadgets to the Internet of Things

The Internet of Things puts intelligence into all kinds of things -- especially in the home, from appliances to light bulbs and door locks. But we still have a ways to go. “We need to be very patient in this category,” says Quirky CEO Ben Kaufman in a conversation with a16z General Partner Scott Weiss. The technology is available, Kaufman adds, we just need our things -- and habits -- to be ready too. So when does this technology go mainstream? What gadget do they think will push it over the edge ... and what might hold it back even longer? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

13 Des 201415min

a16z Podcast: Technology and the Opening of Myanmar

a16z Podcast: Technology and the Opening of Myanmar

After years of being shut off to the world -- Myanmar is opening itself up. Not just across physical borders, but also the digital. What happens when the vast majority of a population suddenly has access to a cell phone, not to mention Facebook? How is technology manifesting itself in the media, in the economy and in the education of a population eager to use the tools it suddenly has access to? What can Myanmar teach the rest of the world about the opportunities that arise, and potential pitfalls, when a wave of new technology crashes down? Joining the discussion is David Madden from non-profit Internews and the founder of the brand-new Phandeeyar: Myanmar Innovation Lab; Aye Moah, founder of Silicon Valley-based startup Baydin (in photo); and Ethan Zuckerman director of the Center for Civic Media at MIT.

8 Des 201433min

a16z Podcast: If Coding is the New Literacy, How Can More People Code?

a16z Podcast: If Coding is the New Literacy, How Can More People Code?

Technology can be an equalizer, especially as new tools democratize the expertise that was previously held only by a limited few. But is coding really the new literacy -- the fourth “r” -- after reading, writing and arithmetic? Should it be? Why does this even matter, and how can coding enable more people?

8 Des 201435min

a16z Podcast: Where the Growth in Cloud and Enterprise Software Really Is (with Marc Benioff)

a16z Podcast: Where the Growth in Cloud and Enterprise Software Really Is (with Marc Benioff)

VCs wouldn't fund Salesforce ("that obviously won't work") when Marc Benioff began. With the cloud a growing part of practically every company, government, organization, and people's lives, a lot's changed since 1999. But what's next? Do enterprise CEOs get (mobile) religion? [Answer: not yet. Benioff thinks there's a ton of opportunity ahead there.] What's happening with international growth, when countries want their own clouds and 90% of enterprise software is bought in just 7 countries?

5 Des 201434min

a16z Podcast: Security’s Wakeup Call

a16z Podcast: Security’s Wakeup Call

The security landscape is changing. Can companies fight back against an increasingly well-armed and sophisticated set of bad players? “I think it is the beginning of a wakeup call,” former deputy secretary of defense Ashton Carter says. “That said, I think there are a lot of people at the top that don’t know what to do.” Carter (who is is expected to be formally nominated as the next Secretary of Defense) joins a16z board partner John Jack and Yahoo security chief Alex Stamos for a wide-ranging discussion about the state of security.

3 Des 201429min

a16z Podcast: Guiding Startup Culture -- The Genius ISMs

a16z Podcast: Guiding Startup Culture -- The Genius ISMs

It might seem that culture at a startup is something that is just intuitive. And in the first days, with the first handful of people, that might be true. But the co-founders of Genius.com, Tom Lehman and Ilan Zechory (pictured), found that even at 25 people taking the time to describe their company's culture in detail -- their basic principles of life and work -- was critical. What follows is their version of a culture guide, the "Genius ISMs," from the practical -- "take the roast out of the oven," and "run into the spike," to the more tonal -- "we'll figure it out" and "the chaos will not be minimized." You can check out all 17 here: http://genius.com/Genius-the-genius-isms-annotated And of course here's the interview annotated: http://genius.com/A16z-genius-podcast-annotated The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

28 Nov 201432min

a16z Podcast: Ecommerce and the Holiday Shopping Collision

a16z Podcast: Ecommerce and the Holiday Shopping Collision

How can ecommerce companies deal with the conflicting expectations of consumers and logistics realities of an on-demand economy? How can they compete with ecommerce giant Amazon, which just gets bigger every year? And given all this, how is physical retail faring? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

21 Nov 201422min

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