Marc Andreessen & Jack Altman: Venture Capital, AI, & Media

Marc Andreessen & Jack Altman: Venture Capital, AI, & Media

In this episode Jack Altman, CEO of Lattice and host of Uncapped, interviews Marc Andreessen on how venture capital is evolving — from small seed funds to billion-dollar barbell strategies — and why today’s most important tech companies don’t just build tools, they replace entire industries. They cover:

  • The end of “picks and shovels” investing
  • Why missing a great company matters more than backing a bad one
  • The power law math behind fund size and asymmetric returns
  • AI as the next computing platform — and a test for Western civilization
  • Preference falsification, media power, and what founders can’t say out loud

This is a conversation about ambition at scale, the structure of modern venture, and the deep forces reshaping startups, innovation, and power.

Resources:

Listen to more from Uncapped: https://linktr.ee/uncappedpod

Find Jack on Xhttps://x.com/jaltma

Find Marc on X: https://x.com/pmarca

Find Uncapped on X: https://x.com/uncapped_pod

Timecodes:
00:00 What You Can’t Say

01:20 Founders, Funders, and the Future

02:00 Fund Size and Power Law Math

06:45 From Tools to Full Stack Startups

10:00 Market Sizing and Asymmetric Bets

13:00 Public Markets Mirror Venture Dynamics

17:00 The Barbell Strategy in Venture

20:00 The Conflict Dilemma in Venture

25:00 Staying in Early-Stage Venture

29:30 The Death of the Middle

32:00 Why It’s So Rare to Build a New Top VC Firm

35:00 The Case for Power in Venture

37:45 Limiting Factors for Big Companies

41:00 AI as the Next Computing Platform

45:30 Betting on Startups, Not Incumbents

48:00 How a16z Thinks About Risk

51:00 Building a Top-Tier GP Team

55:00 Taste, Timing, and Getting Into the Scene

57:00 Raising Capital Is the Easy Part

1:00:30 AI’s Existential Stakes

1:05:00 Autonomous Weapons, Ethics, and War

1:11:00 Tech, Government, and Power

1:13:00 Media, Mistrust, and Narrative Collapse

1:24:00 Preference Falsification and Cultural Cascades

1:32:00 The Thought Experiment

1:33:00 Career Advice for Young Builders

1:35:00 Marc vs. the Huberman Protocol

1:39:30 What Would Prove You Right?

Stay Updated:

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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Episoder(900)

a16z Podcast: Everything You Need to Know About Amazon

a16z Podcast: Everything You Need to Know About Amazon

Profitless Ponzi scheme, or the greatest company in the world led by an absolute genius? Amazon is a polarizing company. Quarter after quarter, as it grows ever larger gobbling up categories and adding businesses, Amazon manages to produce exactly no profit. It’s as if its founder and CEO Jeff Bezos engineered it that way. He has, and Bezos will continue on the same profitless path, says Benedict Evans in conversation with Ben Horowitz in this segment of the a16z podcast. Benedict and Ben (yeah, we know, two Bens) examine the company Bezos has constructed, and why, for Bezos at least as opposed to nervous investors, it works so well. How one of the world's great founders gets away with building a massive public company his way. Be sure to check out Benedict's post on the topic for all the charts and numbers: http://a16z.com

5 Sep 201417min

a16z Podcast: Building Brands and Running Retail -- Ron Johnson and Tristan Walker Break It Down

a16z Podcast: Building Brands and Running Retail -- Ron Johnson and Tristan Walker Break It Down

Given that physical retail is expensive, what’s the right distribution mix for startups? In this podcast with Tristan Walker (who is building health and beauty brand Walker & Company from scratch), we hear Ron Johnson's lessons learned from arguably the world’s most successful physical retail outlet: the Apple Store -- as well as a discussion of the challenges of brand and retail in a multichannel world. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

3 Sep 201427min

a16z Podcast: Three Kids, One App, One Love -- The Five-O Story

a16z Podcast: Three Kids, One App, One Love -- The Five-O Story

Teenage siblings Ima, Asha and Caleb Christian from Atlanta, Georgia join Ben Horowitz for a discussion about the motivation and origins of their new app, Five-O. In the aftermath of the tragedy in Ferguson, Missouri, the young developers built Five-O as a tool to rate and document interactions -- good and bad -- with the police. Ben and the Five-O team discuss the origins and technical underpinnings of the app. Rapper Nas makes an appearance, offering his own experience with the police, and why efforts like Five-O work towards a solution that both citizens and police should get behind. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

28 Aug 201413min

a16z Podcast: Ben and Marc Explain (Practically) Everything – Part 2

a16z Podcast: Ben and Marc Explain (Practically) Everything – Part 2

The five-year anniversary segment with a16z founders Ben Horowitz and Marc Andreessen picks up with a discussion of Clayton Christensen's theories around disruption. Why Christensen's thinking is very much on the mark today, and how his theories help guide the firm in making decisions about what NOT to invest in. Ben offers one of the things he wished he had known as a young CEO, and Marc describes a trait that every great entrepreneur possesses. Part two of two.

26 Aug 201416min

a16z Podcast: Ben and Marc Explain (Practically) Everything – Part 1

a16z Podcast: Ben and Marc Explain (Practically) Everything – Part 1

Around the firm we use “software eats the world” as a guide for how technology will impact every industry and every person – from education to healthcare and government. As a16z marks its five-year anniversary, we turned to the fellow who came up with the thesis, Marc Andreessen, to explain how it’s rippling around the globe. And to break down all the implications for building companies and managing people we tapped a16z's cofounder Ben Horowitz. With both “a” and “z” in the room, this segment takes stock of the technology industry and startup ecosystem – from entrepreneurs to investors, and where it’s all headed next. Part one of two.

25 Aug 201427min

a16z Podcast: The Topic That's Lasted the Entire History of Computing -- Bundling and Unbundling

a16z Podcast: The Topic That's Lasted the Entire History of Computing -- Bundling and Unbundling

Jim Barksdale in the run-up to the Netscape IPO told potential investors that you can make money in software in two ways: bundling and unbundling. Benedict Evans and Steven Sinofsky revisit that thesis in the context of a mobile app world -- how Facebook for example, is unbundling itself, while at the same time Baidu is bundling everything together as fast as it can. How and why Barksdale's thesis is very much alive and well in the mobile world. All that, and the proper use of "fissiparousness" in a sentence.

15 Aug 201419min

a16z Podcast: The Consumerization of IT

a16z Podcast: The Consumerization of IT

Peter Levine goes deeper into the changing nature of the data center with Yoram Novick, CEO of Maxta, and Florian Leibert, CEO of Mesosphere. Does ARM architecture, the foundation of the chips in practically every mobile phone, have what it takes to displace X86 processors in the data center? Is the private cloud --- effectively a company operating its own data center -- dead, or will a hybrid public/private cloud model dominate? Given all the upheaval in the data center how do startups fit into the equation, and how are they competing today with legacy technologies and companies? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

31 Jul 201422min

a16z Podcast: Mobile Invades the Data Center

a16z Podcast: Mobile Invades the Data Center

There is a shift in enterprise hardware from expensive, proprietary hardware to cheap components plucked directly from the consumer hardware supply chain. While that trend has been underway for some time thanks to companies like Google, Facebook and Amazon rolling their own data centers, the next wave of enterprise IT is taking its cues from the mobile supply chain’s collection of components -- the stuff that your mobile phone is made of. That includes everything from power-sipping ARM chips to flash-based memory. Andreessen Horowitz’s Peter Levine is joined by Coho Data CEO Ramana Jonnala and Cumulus Networks CEO JR Rivers for a discussion about the consumerization of the datacenter. Where is the hardware coming from? How will software make it all work? What does it mean for incumbent hardware and software vendors? And how will customers buy all this data center muscle? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.

31 Jul 201425min

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