SNR #123: Donald Layman, PhD - Leucine Kinetics, mTOR Activation & the Anabolic Response to Protein

SNR #123: Donald Layman, PhD - Leucine Kinetics, mTOR Activation & the Anabolic Response to Protein

Episode 123: Donald Layman PhD, professor emeritus at the University of Illinois, discusses the "leucine threshold" and activation of the mTOR pathway, amino acid oxidation and why MPS drops 2-3 hours after that peaking even when protein remains being fed.

Dr. Layman is professor emeritus at the University of Illinois.

Dr. Layman's laboratory is working to define protein and amino acid requirements and the interrelationship between dietary protein and carbohydrates in adult health. His research is focused on the impact of diet and exercise on adult health problems of obesity, type 2 diabetes and the Metabolic Syndrome.

We discuss:
What should we define as a "high-protein" diet?
Making protein recommendations on a per meal basis
The "leucine threshold" and activation of the mTOR pathway
Other metabolic signals triggered off by amino acids that play a role in health
The roles of insulin and leucine in mTOR activation - shifts in their contribution over time
Why oxidation of amino acids does not mean they are "wasted"
Why MPS drops 2-3 hours after that peaking even when protein remains being fed
Protein synthesis as an energy expensive process
Leucine kinetics
Protein leverage hypothesis

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(643)

#620: BPC-157 and Peptide Medications: What Do We Know? – Jordan Feigenbaum, MD

#620: BPC-157 and Peptide Medications: What Do We Know? – Jordan Feigenbaum, MD

Commonly people are talking about "peptides" to refer to a heterogeneous group of peptide medications or investigational compounds. These are increasingly promoted for injury recovery, tissue repair, ...

15 Sep 57min

#619: How Much Fish Should a Healthy Diet Contain?

#619: How Much Fish Should a Healthy Diet Contain?

Most dietary guidelines recommend eating one to two servings of fish per week, often specifying that at least one serving should be oily fish. But how directly is that recommendation supported by evid...

8 Sep 1h 3min

#618: How Wellness & Optimisation Culture Can Commodify Science – Nick Tiller, PhD

#618: How Wellness & Optimisation Culture Can Commodify Science – Nick Tiller, PhD

Wellness and optimisation culture increasingly presents itself as "science-based". But citing studies, using technical language, or having scientific credentials does not guarantee that the underlying...

1 Sep 56min

#617: What Does Effective Athlete Support Look Like in Practice? – Gemma McGuinness

#617: What Does Effective Athlete Support Look Like in Practice? – Gemma McGuinness

Effective athlete support requires more than delivering technically correct nutrition advice. It depends on understanding the athlete's wider environment, anticipating the pressures that disrupt good ...

25 Aug 46min

Fiber: Independent Benefits or Just a Proxy for Healthy Foods?

Fiber: Independent Benefits or Just a Proxy for Healthy Foods?

This episode answers one of the questions raised in the most recent Q&A episode on Sigma Nutrition Premium.  The full episode includes the following questions: Fiber: Independent effect or proxy for ...

18 Aug 21min

#616: More Testing, Better Health? Harms of Overdiagnosis & Overtreatment - Austin Baraki, MD

#616: More Testing, Better Health? Harms of Overdiagnosis & Overtreatment - Austin Baraki, MD

Medical screening is often framed as an uncomplicated good: if disease is found earlier, treatment can begin earlier and outcomes should improve. This episode examines why that reasoning is incomplete...

11 Aug 1h 15min

#615: Why Processing Doesn't Determine the Healthfulness of Plant-Based Diets – Alysha Thompson, PhD

#615: Why Processing Doesn't Determine the Healthfulness of Plant-Based Diets – Alysha Thompson, PhD

What does the evidence actually show when we look at plant-based dietary patterns through the lens of food processing? And does classifying foods as "ultra-processed" meaningfully change how we interp...

4 Aug 56min

#614: The Human Skills of Nutrition Coaching – Krista Scott-Dixon, PhD

#614: The Human Skills of Nutrition Coaching – Krista Scott-Dixon, PhD

In nutrition and health coaching, one of the central challenges is understanding how people actually change, particularly when life is complex, motivation fluctuates, and behaviour is shaped by emotio...

21 Jul 56min

Populært innen Helse

fastlegen
rss-gukild-johaug
psykodrama
hvordan-har-du-det-mann
lydartikler-fra-aftenposten
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
leger-om-livet
rss-skravla-gar
foreldreradet
bak-fasaden-en-reise-i-livet-med-sykepleier-ine
morten-ramm-lar-kakla-ga-til-du-sovner
klimaks
hjernesterk
g-punktet
rss-lopedrommen
rss-kunsten-a-leve
treningsprat
rss-loping-for-nybegynnere
kjed-deg-i-sovn-verdens-kjedeligste-podcast
hverdagspsyken