Atomic Anesthesia13 Okt 2025

PHARMACOGENETICS: WHY DRUG RESPONSES DIFFER IN A POPULATION OF PEOPLE │ EP56

This is a joint episode recorded with Dr. Chloe Gomez of the My Favorite Learner podcast. This episode explores the foundational concepts of pharmacogenetics and its impact on drug responses during anesthesia, highlighting how genetic, genomic, and epigenetic variations shape individual reactions to commonly used medications in perioperative care. Designed for nurse anesthesia residents, the show walks through the scenarios of variable drug response, the roles of metabolizing enzymes, transport molecules, and molecular targets, as well as the influence of environmental factors and polymorphisms such as single-nucleotide variants and ethnic differences in metabolism. Key topics include disease-specific considerations like G6PD deficiency, acute intermittent porphyria, long QT syndrome, Brugada syndrome, atypical pseudocholinesterase, and malignant hyperthermia, with a focus on clinical implications for personalized medicine, precision dosing, and ethical issues surrounding genetic testing, privacy, and patient equity. Practical advice covers vigilant monitoring, individualized dosing, preoperative assessment for genetic risk, and strategies for documenting and communicating findings for safer anesthesia practice.

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Episoder(114)

THE TWITCHING HOUR: TRAIN-OF-FOUR EXPLAINED │ EP114

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

23 Sep 29min

VASODILATORS IN THE OR: WHEN THE PRESSURE NEEDS TO DROP NOW │ EP113

11 Sep 11min

DECODING DEXAMETHASONE'S ANTIEMETIC EFFECT (MECHANISM EXPLAINED) │ EP112

8 Sep 22min

THE DIFFICULT AIRWAY ALGORITHM, STEP-BY-STEP │ EP111

4 Sep 19min

10 HIGH-YIELD SEE/NCE BOARD QUESTIONS EXPLAINED │ EP110

1 Sep 26min

PREECLAMPSIA AND THE OB PATIENT: PATHOPHYSIOLOGY THAT SAVES LIVES │ EP109

21 Aug 10min

CRNA WORKFORCE CHANGES: DO THESE THINGS TO LAND YOUR PERFECT JOB │ EP108

14 Aug 18min

REGIONAL ANESTHESIA 101: BLOCKS EVERY CRNA SHOULD KNOW │ EP107

Regional anesthesia is one of the highest-yield, most heavily tested areas on the boards, but most review content buries the clinically useful details under anatomy that never gets asked. This episode...

13 Aug 14min