A Dose of Reality with Charles Spence

A Dose of Reality with Charles Spence

Welcome to “A Dose of Reality”, the podcast where we infuse insight, laughter, and practical wisdom into the world of clinical leadership and career development. Hosted by Charles Spence, each episode offers a deep dive into the challenges and triumphs of clinical leadership, providing listeners with meaningful conversations, career insights, and a dose of inspiration to navigate their professional journeys. Whether you're a director, a C-level executive, or a clinical researcher in oncology bio-techs, this podcast is designed to empower you with the knowledge and tools needed to excel in your field. So, visit our website at www.discera-search.com, and tune in to A Dose of Reality for your prescription of career wisdom, leadership insights, and a healthy dose of laughter. Subscribe now and join us on the journey to becoming global clinical leaders!

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Episoder(75)

Bernhardt Zeiher, M.D.  Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization

Bernhardt Zeiher, M.D. Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization

In this episode, I talked with Dr. Bernhardt (Bernie) Zeiher, where he shares key lessons and personal insights from over 25 years in pharmaceutical drug development. Bernie discusses pivotal career m...

30 Jun 202534min

Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works

Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works

In this episode, I talked with Dr. Ilya Gipp, Chief Medical Officer at GE Healthcare, where he shares lessons from a career spent at the intersection of clinical medicine and medtech leadership. He ta...

16 Jun 202538min

Michael Lahn, CMO at iOnctura – Osimertinib Success, TGF-Beta Lessons, Building Curious Teams, and More

Michael Lahn, CMO at iOnctura – Osimertinib Success, TGF-Beta Lessons, Building Curious Teams, and More

In this conversation, I talked with Michael Lahn, Chief Medical Officer of Ionctura, a clinical-stage biotech focusing on therapies for neglected and hard-to-treat cancers, where he shared his insight...

9 Jun 202531min

Johan Baeck, EVP and CMO at Promontory Therapeutics – Cultural Fit in Hiring, Immunogenic Small Molecules, and Building Resilience in Biotech

Johan Baeck, EVP and CMO at Promontory Therapeutics – Cultural Fit in Hiring, Immunogenic Small Molecules, and Building Resilience in Biotech

In this episode, I talked with Johan Baeck, Executive Vice President and Chief Medical Officer at Promontory Therapeutics, a clinical-stage biotech focused on developing novel small molecule immunogen...

28 Mai 202532min

Peter Tummino, President of R&D at Nimbus Therapeutics – Drugging the Undruggable, The TYK2 Success Story, and Overhyping AI in Drug Discovery

Peter Tummino, President of R&D at Nimbus Therapeutics – Drugging the Undruggable, The TYK2 Success Story, and Overhyping AI in Drug Discovery

In this episode, I talked with Peter Tummino, President of Research and Development at Nimbus Therapeutics, where he discussed what it takes to build a successful biotech R&D engine. Peter shares his ...

12 Mai 202527min

Abigail Jenkins, CEO and Board Member – From Government Scientist to CEO, Launching a Stem Cell Therapy During Crisis, and Lessons in Commercial Strategy

Abigail Jenkins, CEO and Board Member – From Government Scientist to CEO, Launching a Stem Cell Therapy During Crisis, and Lessons in Commercial Strategy

In this episode, I talked with Abigail (Abbey) Jenkins, a pharmaceutical executive with 25+ years of experience, who shares her career journey, highlighting her entry into the industry, proud achievem...

6 Mai 202532min

Joseph Birkett, Executive Director at Aura Biosciences – Obinutuzumab's Approval, CDK9 Trial Regret, CRO Reliance, and Building Respectful Cultures

Joseph Birkett, Executive Director at Aura Biosciences – Obinutuzumab's Approval, CDK9 Trial Regret, CRO Reliance, and Building Respectful Cultures

Joseph (Joe) Birkett, Executive Director of Medical Affairs at Aura Biosciences, joined our podcast to share what he’s learned over two decades in oncology drug development, including the career-defin...

27 Apr 202533min

Bruce Dezube, Senior Vice President, Clinical Development at Xilio Therapeutics – HIV & Cancer Drug Development, Career at 60, Building Respectful Teams, and More

Bruce Dezube, Senior Vice President, Clinical Development at Xilio Therapeutics – HIV & Cancer Drug Development, Career at 60, Building Respectful Teams, and More

In this episode, I talked with Dr. Bruce Dezube, Senior Vice President, Clinical Development of Xilio Therapeutics, a clinical-stage biotechnology company focused on developing tumor-activated immuno-...

22 Apr 202532min

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