The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1583)

What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447

What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447

My favorite creatine (discount code DAVETUBE): https://www.qualialife.com/ASPREYRECOMMENDSCreatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain opt...

12 Apr 30min

Superhuman Contact Lenses, Motivation Supplement Stack, Cat Scratches Cause Brain Fog, Amino Acid Shortening Lifespan, and more...  : 1448

Superhuman Contact Lenses, Motivation Supplement Stack, Cat Scratches Cause Brain Fog, Amino Acid Shortening Lifespan, and more... : 1448

This week's stories: *Bartonella Hides in Cat Scratches — and It Might Be Why You Feel Like Garbage A stealth bacterial infection transmitted by everyday cat scratches and flea dirt has been quietly l...

10 Apr 9min

Why Doctors Can't Fix Women in 2026 : 1446

Why Doctors Can't Fix Women in 2026 : 1446

Most women are suffering for years from anxiety, gut problems, low libido, and brain fog because no one is treating the real cause: their hormones. This episode is a masterclass in women's hormone opt...

9 Apr 1h 12min

Fix Mitochondria With NASA’s Secret Anti-Aging Superfood : 1442

Fix Mitochondria With NASA’s Secret Anti-Aging Superfood : 1442

I spent over $2 million hacking my own biology to reverse my age, but one of the most powerful discoveries didn’t come from a pharmaceutical lab. It came from NASA.Try Danger Coffee: https://dangercof...

5 Apr 18min

Your AC Is Making You Dumber : 1444

Your AC Is Making You Dumber : 1444

Your home could be quietly stealing your IQ, disrupting your hormones, destroying your mitochondria, and triggering chronic disease, and most people never connect the dots. This episode gives you the ...

3 Apr 54min

Your Doctor Is Wrong About Autism (Here's How To Reverse It) : 1443

Your Doctor Is Wrong About Autism (Here's How To Reverse It) : 1443

Autism is reversible, and the science to prove it already exists. This episode delivers a master class on the biological roots of autism, what actually triggers it, and the protocols that have helped ...

2 Apr 55min

Your Organic Protein Powder Is Slowly Killing You  : 1441

Your Organic Protein Powder Is Slowly Killing You : 1441

Most people buying "clean" supplements are unknowingly loading their bodies with heavy metals, rancid fish oil, and glyphosate, even inside products labeled organic and healthy. This episode breaks do...

31 Mar 1h 2min

This Legal Sleep Powder Beats Melatonin Every Time : 1440

This Legal Sleep Powder Beats Melatonin Every Time : 1440

Try TrueDark (with my discount): https://truedark.com/discount/DAVETUBEI have spent 20 years and over $2 million testing my biology, and the biggest lesson I've learned is that sleep is a neurological...

29 Mar 15min

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