The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1583)

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

This week’s stories: Smartphone App Catches What Sleep Trackers Miss A 2026 trial found that suvorexant, a popular prescription sleep drug, improves sleep quality scores — but worsens morning alertnes...

13 Mar 12min

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it. -Watch this episode on YouTube for the full video experience: h...

12 Mar 1h 3min

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

What if understanding how AI thinks could reveal uncomfortable truths about how your own brain works, and give you powerful tools to make smarter decisions, resist manipulation, and upgrade your cogni...

10 Mar 57min

How I Finally FIXED My Terrible Sleep After 18 Years  : 1428

How I Finally FIXED My Terrible Sleep After 18 Years : 1428

Block toxic light with these glasses: https://truedark.com/discount/DAVETUBEThink 8 hours of sleep is enough? Think again. I used to think I had a sleep issue—turns out, it was a light issue. In this ...

8 Mar 9min

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

This week’s stories: Healthy Diets That Offset "Bad Genes" A major UK Biobank study of over 100,000 people found that following any one of five healthy dietary patterns was associated with up to 3 ext...

6 Mar 11min

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Microplastics are invading your brain, blood, hormones, and fat tissue, and most people have no idea how deep the damage goes. In this episode, Host Dave Asprey and microplastics expert Josephine Musc...

5 Mar 56min

Why Are Hackers Microdosing “Sex Drugs” Now?  : 1425

Why Are Hackers Microdosing “Sex Drugs” Now? : 1425

Most doctors treat the average patient. But you are not average, and this episode gives you the precision medicine blueprint to treat yourself like the individual you are, using multi-omic testing, bi...

3 Mar 53min

A-List Celebrities' Anti-Aging Hack to Look 30 At 50 (Drug-free) : 1424

A-List Celebrities' Anti-Aging Hack to Look 30 At 50 (Drug-free) : 1424

What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And what could lobsters possibly teach us about staying young?Scientists have discovered a remarkable connection ...

1 Mar 14min

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