Orphan Drugs
99% Invisible14 Nov 2018

Orphan Drugs

We chronicle the epic struggle to get drugs that treat very rare diseases on the market, and the unintended consequence of that fight, which affected the cost of all kinds of drugs. This is a strange story that involves a hit 70s TV show, a fake march on Washington, a courageous advocate, a carnival concessions wholesaler, and a new drug law that helped a lot of people, made drug companies billions of dollars, and opened a whole can of worms.

Adapted from the new podcast An Arm and a Leg by Dan Weissmann

Orphan Drugs

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Half a House

Half a House

On the night of February 27th, 2010, a magnitude of 8.8 earthquake hit Constitución, Chile and it was the second biggest that the world had seen in half a century. The quake and the tsunami it produced completely crushed the … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

11 Okt 201618min

Project Cybersyn

Project Cybersyn

On September 11, 1973, a military junta violently took control of Chile, which was led at the time by President Salvador Allende. Allende had become president in a free and democratic election. After the military coup, General Augusto Pinochet took … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

4 Okt 201621min

Longbox (Repeat)

Longbox (Repeat)

Reporter Whitney Jones argues that R.E.M.’s Out of Time is the most politically significant album in the history of the United States. Because of its packaging. Longbox Please Vote. Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

27 Sep 201618min

The Trend Forecast

The Trend Forecast

Who decides that the color this season is “mint green” or that denim jackets are “back?” Of course, there’s top-down fashion, where couture houses and runway shows set a trend that trickles down through the rest of the industry. Then … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

20 Sep 201615min

Making Up Ground

Making Up Ground

Large portions of San Francisco, New York City, Boston, Seattle, Hong Kong and Marseilles were built on top of human made land. What is now Mumbai, India, was transformed by the British from a seven-island archipelago to one contiguous strip … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

13 Sep 201618min

Public Works

Public Works

Infrastructure makes modern civilization possible. Roads, power grids, sewage systems and water networks all underpin society as we know it, forming the basis of our built environment … at least when they work. As Henry Petroski documents in The Road … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

6 Sep 201613min

On Average

On Average

In many ways, the built world was not designed for you. It was designed for the average person. Standardized tests, building codes, insurance rates, clothing sizes, The Dow Jones – all these measurements are based around the concept of an … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

23 Aug 201617min

Photo Credit

Photo Credit

Founded by architect Walter Gropius in 1919, the Bauhaus school in Germany would go on to shape modern architecture, art, and design for decades to come. The school sought to combine design and industrialization, creating functional things that could be … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

17 Aug 201618min

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