Carnivore
2 Keto Dudes12 Dec 2016

Carnivore

Carl Franklin and Richard Morris talk to Amber O'Hearn about being a carnivore, evolution, sleep, ketogenic metabolism, and a few other tasty nuggets you won't want to miss! Errata Richard forgot to mention when working with Transglutaminase .. wear food prep gloves. Amber sent us a piece of errata. She writes: In our podcast, Carl asks me if babies *have* to be in ketosis to build brains, and I say yes, but that's not true. That is, the primary way that babies build fat and cholesterol in the brain in normal conditions *is* out of ketone bodies, though a small proportion is also made from glucose. I have a few references on this point in the talk transcript on my blog. The critical question is: What happens if there are no ketones to be had and only glucose? The answer seems to be that glucose will suffice. There is a rare inborn error of metabolism called HMG-CoA lyase deficiency, which prevents the body from making ketones. A paper by another brilliant Morris ( Cerebral ketone body metabolism ) reports that people afflicted with this have white matter abnormalities, but no noticeable loss of function, except of course, they can't go without food for long. This suggests that in cases where there are no circulating ketones, the glucose alternative pathway will take over, and get at least an adequate brain constructed. It occurs to me that children with this condition may be perfect candidates for the therapeutic use of ketones esters, provided the condition doesn't somehow prevent their use. "Given the importance of KBs [ketone bodies] as substrates for myelination, one might expect disorders of ketogenesis to be associated with cerebral white-matter abnormalities. Magnetic resonance imaging has, indeed, shown diffuse mildly increased signal in the white matter of patients with HMG-CoA lyase deficiency. Superimposed on this are foci of more abnormal signal. In most cases, multiple lesions have been present, varying in size from a few millimetres to large confluent areas; as well as in the cerebral hemispheres, they have been reported in the internal capsule and brainstem but not in the corpus callosum or cerebellar white matter. Despite the imaging abnormalities, most patients have had no neurological problems and normal or slightly below average intelligence. The findings would be compatible with hypomyelination, caused by the lack of KB." Support this podcast at — https://redcircle.com/2-keto-dudes/donations

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The History of Dietary Guidelines with Gary Fettke

The History of Dietary Guidelines with Gary Fettke

Carl Franklin and Richard Morris talk to Dr. Gary Fettke. This time, he uncovers some of the individuals in the United States who have influenced the US dietary guidelines. You may want to sit down before listening. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

13 Aug 20171h 4min

The Dudes Fix Diabetes

The Dudes Fix Diabetes

Carl and Richard talk about their new effort to bring a type 2 diabetes intervention to groups all over the world. The intervention is not just about saving lives, but about the economic impact of metabolic syndrome. Metabolic syndrome has been proven to be at the root of type 2 diabetes, obesity, heart disease, and micro-vascular diseases like kidney disease and ED. What is the burden to the economy? How much money (and how many lives) can be saved by adopting the ketogenic lifestyle? Support this podcast at — https://redcircle.com/2-keto-dudes/donations

7 Aug 201741min

Richard David Feinman at Ketofest 2017

Richard David Feinman at Ketofest 2017

While at Ketofest, Carl and Richard sat down with professor Richard David Feinman for a chat about biochemistry, cancer, and reducing carbohydrates as the first line of defense against the diseases of civilization. They also talk about the success of Ketofest, and what they intend to do in 2018! Support this podcast at — https://redcircle.com/2-keto-dudes/donations

31 Juli 201759min

Doing Science at Ketofest with Dave Feldman

Doing Science at Ketofest with Dave Feldman

Carl and Richard talk to Dave Feldman about the LDL experiment he did with 22 people during Ketofest weekend. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

23 Juli 201739min

Dr. Jeffry Gerber Speaks

Dr. Jeffry Gerber Speaks

Hosts Richard Morris and Carl Franklin talk to Dr. Jeffry Gerber, MD. about his experiences treating patients with low-carb and ketogenic diets. He is very critical of the AHA (American Heart Association) and the conventional ideas that keep being re-hashed. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

10 Juli 20171h 4min

HEAL Thyself with Melanie Miller

HEAL Thyself with Melanie Miller

Carl and Richard talk to Melanie Miller about working for Dr. Eric Westman's HEAL Clinic. Melanie's positive attitude is infectious, and her message is on point. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

3 Juli 20171h 8min

Bad Science with Nick Mailer

Bad Science with Nick Mailer

Carl and Richard talk to Nick Mailer about bad science: how to recognize it and avoid it. Nick gives many examples of how we have been conditioned through language to accept bogus claims. The source of this bias may surprise you. Errata Richard mentioned he visited a Sydney Meat-up hosted by Julie and her husband .. he meant to say Linda. Apologies Also after the podcast was recorded, Richard listened to a podcast by Dr Chris Masterjohn that gave an heroic dismantling of the AHA coconut oil press release and the studies behind it. We've linked THAT in the show notes. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

25 Juni 20171h 4min

The Salt Fix with Dr. James DiNicolantonio

The Salt Fix with Dr. James DiNicolantonio

Richard and Carl talk to Dr. James DiNicolantonio about salt, and how we got it all wrong, from blood pressure to heart disease. Support this podcast at — https://redcircle.com/2-keto-dudes/donations

19 Juni 201758min

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