2025 Highlight-o-thon: Oops! All Bests

2025 Highlight-o-thon: Oops! All Bests

It’s that magical time of year once again — highlightapalooza! Stick around for one top bit from each episode we recorded this year, including:

  • Kyle Fish explaining how Anthropic’s AI Claude descends into spiritual woo when left to talk to itself
  • Ian Dunt on why the unelected House of Lords is by far the best part of the British government
  • Sam Bowman’s strategy to get NIMBYs to love it when things get built next to their houses
  • Buck Shlegeris on how to get an AI model that wants to seize control to accidentally help you foil its plans

…as well as 18 other top observations and arguments from the past year of the show.

Links to learn more, video, and full transcript: https://80k.info/best25

It's been another year of living through history, whether we asked for it or not. Luisa and Rob will be back in 2026 to help you make sense of whatever comes next — as Earth continues its indifferent journey through the cosmos, now accompanied by AI systems that can summarise our meetings and generate adequate birthday messages for colleagues we barely know.

Chapters:

  • Cold open (00:00:00)
  • Rob's intro (00:02:35)
  • Helen Toner on whether we're racing China to build AGI (00:03:43)
  • Hugh White on what he'd say to Americans (00:06:09)
  • Buck Shlegeris on convincing AI models they've already escaped (00:12:09)
  • Paul Scharre on a personal experience in Afghanistan that influenced his views on autonomous weapons (00:15:10)
  • Ian Dunt on how unelected septuagenarians are the heroes of UK governance (00:19:06)
  • Beth Barnes on AI companies being locally reasonable, but globally reckless (00:24:27)
  • Tyler Whitmer on one thing the California and Delaware attorneys general forced on the OpenAI for-profit as part of their restructure (00:28:02)
  • Toby Ord on whether rich people will get access to AGI first (00:30:13)
  • Andrew Snyder-Beattie on how the worst biorisks are defence dominant (00:34:24)
  • Eileen Yam on the most eye-watering gaps in opinions about AI between experts and the US public (00:39:41)
  • Will MacAskill on what a century of history crammed into a decade might feel like (00:44:07)
  • Kyle Fish on what happens when two instances of Claude are left to interact with each other (00:49:08)
  • Sam Bowman on where the Not In My Back Yard movement actually has a point (00:56:29)
  • Neel Nanda on how mechanistic interpretability is trying to be the biology of AI (01:03:12)
  • Tom Davidson on the potential to install secret AI loyalties at a very early stage (01:07:19)
  • Luisa and Rob discussing how medicine doesn't take the health burden of pregnancy seriously enough (01:10:53)
  • Marius Hobbhahn on why scheming is a very natural path for AI models — and people (01:16:23)
  • Holden Karnofsky on lessons for AI regulation drawn from successful farm animal welfare advocacy (01:21:29)
  • Allan Dafoe on how AGI is an inescapable idea but one we have to define well (01:26:19)
  • Ryan Greenblatt on the most likely ways for AI to take over (01:29:35)
  • Updates Daniel Kokotajlo has made to his forecasts since writing and publishing the AI 2027 scenario (01:32:47)
  • Dean Ball on why regulation invites path dependency, and that's a major problem (01:37:21)


Video and audio editing: Dominic Armstrong, Milo McGuire, Luke Monsour, and Simon Monsour
Music: CORBIT
Coordination, transcripts, and web: Katy Moore

Episoder(333)

#20 - Bruce Friedrich on inventing outstanding meat substitutes to end speciesism & factory farming

#20 - Bruce Friedrich on inventing outstanding meat substitutes to end speciesism & factory farming

Before the US Civil War, it was easier for the North to morally oppose slavery. Why? Because unlike the South they weren’t profiting much from its existence. The fight for abolition was partly won bec...

19 Feb 20181h 18min

#19 - Samantha Pitts-Kiefer on working next to the White House trying to prevent nuclear war

#19 - Samantha Pitts-Kiefer on working next to the White House trying to prevent nuclear war

Rogue elements within a state’s security forces enrich dozens of kilograms of uranium. It’s then assembled into a crude nuclear bomb. The bomb is transported on a civilian aircraft to Washington D.C, ...

14 Feb 20181h 4min

#18 - Ofir Reich on using data science to end poverty & the spurious action-inaction distinction

#18 - Ofir Reich on using data science to end poverty & the spurious action-inaction distinction

Ofir Reich started out doing math in the military, before spending 8 years in tech startups - but then made a sharp turn to become a data scientist focussed on helping the global poor. At UC Berkeley...

31 Jan 20181h 18min

#17 - Will MacAskill on moral uncertainty, utilitarianism & how to avoid being a moral monster

#17 - Will MacAskill on moral uncertainty, utilitarianism & how to avoid being a moral monster

Immanuel Kant is a profoundly influential figure in modern philosophy, and was one of the earliest proponents for universal democracy and international cooperation. He also thought that women have no ...

19 Jan 20181h 52min

#16 - Michelle Hutchinson on global priorities research & shaping the ideas of intellectuals

#16 - Michelle Hutchinson on global priorities research & shaping the ideas of intellectuals

In the 40s and 50s neoliberalism was a fringe movement within economics. But by the 80s it had become a dominant school of thought in public policy, and achieved major policy changes across the Englis...

22 Des 201755min

#15 - Phil Tetlock on how chimps beat Berkeley undergrads and when it’s wise to defer to the wise

#15 - Phil Tetlock on how chimps beat Berkeley undergrads and when it’s wise to defer to the wise

Prof Philip Tetlock is a social science legend. Over forty years he has researched whose predictions we can trust, whose we can’t and why - and developed methods that allow all of us to be better at p...

20 Nov 20171h 24min

#14 - Sharon Nunez & Jose Valle on going undercover to expose animal abuse

#14 - Sharon Nunez & Jose Valle on going undercover to expose animal abuse

What if you knew that ducks were being killed with pitchforks? Rabbits dumped alive into containers? Or pigs being strangled with forklifts? Would you be willing to go undercover to expose the crime? ...

13 Nov 20171h 25min

#13 - Claire Walsh on testing which policies work & how to get governments to listen to the results

#13 - Claire Walsh on testing which policies work & how to get governments to listen to the results

In both rich and poor countries, government policy is often based on no evidence at all and many programs don’t work. This has particularly harsh effects on the global poor - in some countries governm...

31 Okt 201752min

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