JAMA Clinical Reviews

JAMA Clinical Reviews

Author interviews that explore the latest clinical reviews.

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Episoder(500)

How Couples With Genetic Disease Can Have Healthy Offspring

How Couples With Genetic Disease Can Have Healthy Offspring

Clinicians can now sample DNA from in vitro blastocysts to identify embryos with genetic abnormalities and avoid implanting them. This genetic screening allows couples who carry dangerous genetic dise...

5 Sep 201715min

Are they safe? Drugs and devices receiving accelerated approval by the FDA

Are they safe? Drugs and devices receiving accelerated approval by the FDA

Some drugs and devices receive accelerated approval from the FDA in order to provide potentially important treatments for patients when effective therapies may not be available. These drugs or devices...

15 Aug 201727min

How Studying Familial Hypercholesterolemia Resulted in the Discovery of Statins as an Effective Treatment for High Cholesterol

How Studying Familial Hypercholesterolemia Resulted in the Discovery of Statins as an Effective Treatment for High Cholesterol

Scott Grundy, MD, PhD, is a professor of medicine at UT Southwestern in Dallas and is one of a small group of investigators who saved statins from being dumped as a potential drug class. Dr Grundy tel...

25 Jul 201720min

How to Diagnose and Manage Adult Asthma

How to Diagnose and Manage Adult Asthma

Asthma often develops in childhood but also affects a significant number of adults. It can present in various ways and with varying degrees of severity. William J. Calhoun, MD, of the University of Te...

18 Jul 201733min

Dual Antiplatelet Therapy: Balancing Ischemic and Bleeding Risk

Dual Antiplatelet Therapy: Balancing Ischemic and Bleeding Risk

Following placement of cardiac stents, patients receive dual antiplatelet therapy (DAPT) to prevent stent thrombosis. Prevention of thrombosis is offset by a risk of bleeding. The optimal balance betw...

11 Jul 201728min

Penicillin Allergy – It's Less Common Than You Think

Penicillin Allergy – It's Less Common Than You Think

Allergy to penicillin is one of the most commonly reported allergies by patients. In reality, true penicillin allergy is uncommon. Dr. Elizabeth Phillips from Vanderbilt University discusses her exper...

3 Jul 201720min

Diagnosing Congenital and Intellectual Abnormalities With Chromosomal Microarray Analysis

Diagnosing Congenital and Intellectual Abnormalities With Chromosomal Microarray Analysis

Chromosomal microarray technology (CMA) facilitates the genetic diagnosis of intellectual disabilities, autism spectrum disorder, and congenital abnormalities in children. Previously, G-band karyotypi...

27 Jun 201718min

High-Intensity Statin Therapy – The Controversy Continues

High-Intensity Statin Therapy – The Controversy Continues

Multiple guidelines have been issued regarding how aggressively cholesterol should be managed. These guidelines do not agree with one another and the most significant area of disagreement is in recomm...

27 Jun 201735min

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