The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1585)

Boost Brain Power by 25% WITHOUT a Pill (Brain Optimization Secrets)  : 1305

Boost Brain Power by 25% WITHOUT a Pill (Brain Optimization Secrets) : 1305

You’re leaving brainpower on the table, and this episode shows you how to reclaim it. Learn how to boost cognitive performance by 25% without relying on pills, stimulants, or gimmicks. Host Dave Aspre...

24 Jul 20251h 10min

The Biohacking Tool That Will Change the World (Mitochondrial Transfusions)  : 1304

The Biohacking Tool That Will Change the World (Mitochondrial Transfusions) : 1304

This may be the most cutting-edge life extension technology you’ll hear about for decades. You’ll discover how mitochondrial transfusion, rejuvenation, and repair could reverse biological aging, super...

22 Jul 202554min

The Fastest-Acting Nootropic I’ve Ever Used  : 1303

The Fastest-Acting Nootropic I’ve Ever Used : 1303

What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glu...

18 Jul 202546min

Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway) : 1302

Why Big Pharma Hates Nitric Oxide (And How to Use It Anyway) : 1302

If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal wh...

17 Jul 202553min

Easy Oxygen Hacking for Mitochondria (The 15-Minute Upgrade)  : 1301

Easy Oxygen Hacking for Mitochondria (The 15-Minute Upgrade) : 1301

Supercharge your mitochondria, slash inflammation, and boost energy with one of the most overlooked hacks in human performance. This episode reveals how just 15 minutes of oxygen-based exercise can ra...

15 Jul 202549min

Facelifts, Breast Implants, and the REAL Fix for Wrinkles  : 1300

Facelifts, Breast Implants, and the REAL Fix for Wrinkles : 1300

Wrinkles are just the surface. This episode reveals what’s really happening beneath your skin and how to reverse it using stem cells, regenerative medicine, and the most advanced techniques in plastic...

10 Jul 202557min

Superintelligence, Transhumanism & Biohacking in 2027 : 1299

Superintelligence, Transhumanism & Biohacking in 2027 : 1299

Superintelligence is coming faster than anyone predicted. In this episode, you’ll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. ...

8 Jul 20251h 17min

Why I Add Creatine to My Coffee Every Morning (And You Should Too)  : 1298

Why I Add Creatine to My Coffee Every Morning (And You Should Too) : 1298

Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episod...

3 Jul 202530min

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