The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1585)

Death, Legacy & the Philosophy of Longevity — with Stephen Cave : 1297

Death, Legacy & the Philosophy of Longevity — with Stephen Cave : 1297

What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why s...

1 Jul 202557min

Fix What’s Making You Feel Old—From Joints to Mitochondria | Dr. Greg Kelly  : 1296

Fix What’s Making You Feel Old—From Joints to Mitochondria | Dr. Greg Kelly : 1296

You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden c...

27 Jun 202545min

The Ultimate Guide to a Metabolism That Burns Fat Again  — with Ben Azadi : 1295

The Ultimate Guide to a Metabolism That Burns Fat Again — with Ben Azadi : 1295

93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap ...

26 Jun 20251h 6min

Why Your Workouts Aren’t Giving You a Summer Body — with Nick Bare  : 1294

Why Your Workouts Aren’t Giving You a Summer Body — with Nick Bare : 1294

You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do inste...

24 Jun 202549min

The Plants That Reverse Aging And Block Daily Toxins — with Darin Olien : 1293

The Plants That Reverse Aging And Block Daily Toxins — with Darin Olien : 1293

Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxi...

19 Jun 20251h 5min

The Anti-Aging Skincare Trends That Are DAMAGING Your Skin | Amitay Eshel  : 1292

The Anti-Aging Skincare Trends That Are DAMAGING Your Skin | Amitay Eshel : 1292

Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapi...

17 Jun 20251h 8min

Why Most Supplements Are a WASTE of Money (And What Actually Works)  : 1291

Why Most Supplements Are a WASTE of Money (And What Actually Works) : 1291

Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the need...

13 Jun 202543min

Can Injectable MDMA Become the Next Biohack in 2026? RFK Jr. vs FDA  – Rick Doblin  : 1290

Can Injectable MDMA Become the Next Biohack in 2026? RFK Jr. vs FDA – Rick Doblin : 1290

Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutica...

12 Jun 202553min

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