The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1588)

How Gut Bacteria Can Change Your Weight & Metabolism – Colleen Cutcliffe, Ph.D. : 1004

How Gut Bacteria Can Change Your Weight & Metabolism – Colleen Cutcliffe, Ph.D. : 1004

Pendulum sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a re...

13 Des 202244min

Why Youth Mental Health & Suicide Matters to Everyone – Dr. Mark Goulston : 1003

Why Youth Mental Health & Suicide Matters to Everyone – Dr. Mark Goulston : 1003

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very ...

9 Des 20221h 1min

How to Do the Work, Meet Your Self and Be Your Most Authentic – Nicole LePera, Ph.D. : 1002

How to Do the Work, Meet Your Self and Be Your Most Authentic – Nicole LePera, Ph.D. : 1002

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips.Using the tenants of holistic psych...

6 Des 202248min

Discovering Blue Zones In America – Dan Buettner : 1001

Discovering Blue Zones In America – Dan Buettner : 1001

IN THIS EPISODE OF THE HUMAN UPGRADE™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and w...

2 Des 202249min

The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. : 1000

The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. : 1000

(ZBiotics sponsored this episode.)IN THIS EPISODE OF THE HUMAN UPGRADE™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-...

29 Nov 202255min

Mini-Episode: Cool Facts Friday #29

Mini-Episode: Cool Facts Friday #29

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a mon...

25 Nov 20228min

How Urolithin A Helps Create Super T-Cells & Boosts Immunity – Dr. Anurag Singh : 999

How Urolithin A Helps Create Super T-Cells & Boosts Immunity – Dr. Anurag Singh : 999

Timeline Nutrition sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin...

22 Nov 202250min

Battling Pathogens and Building Immunity Begins In Your Gut – Dr. Robynne Chutkan : 998

Battling Pathogens and Building Immunity Begins In Your Gut – Dr. Robynne Chutkan : 998

IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. Y...

18 Nov 20221h 17min

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